CAJ | 학술논문

目的：探讨咪达唑仑复合丙泊酚静脉麻醉用于无痛胃镜的临床效果及安全性。方法：收集本院无痛胃镜检查的患者共300例，随机分为观察组（A组）与对照组（B组），A组在异丙酚1.5～2.5mg/kg+咪达唑仑0.01～0.05mg/kg，B组单用异丙酚1.5～2.5mg/kg麻醉。比较两组患者的术前及给药后的HR、MAP、SPO2；苏醒时间；异丙酚用量的差异，术后询问患者的遗忘程度及满意度。结果：300例患者均完成胃镜检查，安全离院。与A组相比，B组的患者的遗忘程度及满意度上无明显差异（P>0.05），但B组生命体征的波动小于A组（P<0.05），且苏醒时间长于A组有统计学意义（P<0.05），丙泊酚的用量明显少于A组有统计学意义（P<0.05）不良反应B组也明显多于A组有统计学意（P<0.05）。结论：咪达唑仑复合丙泊酚应用于胃镜检查是一项安全、可靠、无痛的检查方法，值得临床推广。
목적：탐토미체서륜복합병박분정맥마취용우무통위경적림상효과급안전성。방법：수집본원무통위경검사적환자공300례，수궤분위관찰조（A조）여대조조（B조），A조재이병분1.5～2.5mg/kg+미체서륜0.01～0.05mg/kg，B조단용이병분1.5～2.5mg/kg마취。비교량조환자적술전급급약후적HR、MAP、SPO2；소성시간；이병분용량적차이，술후순문환자적유망정도급만의도。결과：300례환자균완성위경검사，안전리원。여A조상비，B조적환자적유망정도급만의도상무명현차이（P>0.05），단B조생명체정적파동소우A조（P<0.05），차소성시간장우A조유통계학의의（P<0.05），병박분적용량명현소우A조유통계학의의（P<0.05）불량반응B조야명현다우A조유통계학의（P<0.05）。결론：미체서륜복합병박분응용우위경검사시일항안전、가고、무통적검사방법，치득림상추엄。
Objective :To explore the effect,safety and value of propofol combined with midazolam in painless gastrointestinal endoscopy. Methods: 300 patients of our hospital were collected and divided into group A (n=150 ,infusion with midazolam 0.01~0.05mg/kg +infhsion with propoful1.5~2.5mg/kg 5 min later) and group B (n=150, infusion with infhsion with propoful 1.5~2.5mg/kg),The mean anterial pressure(MAP),heart rate(HR)and pulse oxygen satufation(SpO2)were obtained before infusion,aner disappearance of eyelash reflex, and the time for regaining eonsciousness, propofol dosage, and were also retcorded..Results:300 case of patients were able to complete the gastrointescopy examination successfully with no serious side effect,Compared with group A, The patients of group B were no significant diffent in satisfaction and degree of forgetting (P>0.05),But the MAP、HR、SpO2 is chang more obvious in group A (P<0.05), the eyeopening time were longer in group B(P<0.05), adverse reaction were lesser in group B(P<0.05)and the consumed dose of propofo1 were lower in group B (P<0.05).Conclusion:Propofol combined witIl midazolam in painless gastrointescopy was a safe,effective and painless ,process and was worthy of promoting widely.