CAJ | 학술논문

本文从仿生角度出发，模拟细胞外基质独特结构，采用静电纺丝法成功制备出HA均匀分布的HA/Ge-latin复合纤维。根据影响静电纺丝的主要因素，分别考察了聚合物浓度、无机物含量、溶剂浓度、电纺电压等因素对纤维形貌和结构的影响。研究结果表明：聚合物浓度是制备复合纤维的首要影响因素，影响复合纤维的直径；无机物的添加使聚合物中的氢键减少，降低了电纺液的粘度，影响复合纤维中珠状物的形成；制备分布均匀的电纺纤维，溶剂起很大的作用，影响纤维的粘联；电纺电压增大使电场力过大，聚合物被强力拉伸，单根纤维出现卷曲。
본문종방생각도출발，모의세포외기질독특결구，채용정전방사법성공제비출HA균균분포적HA/Ge-latin복합섬유。근거영향정전방사적주요인소，분별고찰료취합물농도、무궤물함량、용제농도、전방전압등인소대섬유형모화결구적영향。연구결과표명：취합물농도시제비복합섬유적수요영향인소，영향복합섬유적직경；무궤물적첨가사취합물중적경건감소，강저료전방액적점도，영향복합섬유중주상물적형성；제비분포균균적전방섬유，용제기흔대적작용，영향섬유적점련；전방전압증대사전장력과대，취합물피강력랍신，단근섬유출현권곡。
In the present study,hydroxyapatite( HA)/Gelatin composite fibers have been prepared by electrospinning,which mimics the unique structure of extracellular matrix. HA were uniformly distributed in the files. The influences of electrospinning parameters, such as polymer concentration,inorganic content,solvent concentration,and electrospun voltage,on fiber morphology and structure have been investigated. The results show that polymer concentration is the primary factor that affects the diameter of the fibers. The addition of inorganic HA particles reduces the hydrogen bonding in polymer,decreases the viscosity of electrospinning liquid,and results in the bead-like fibers. Solvent is the main factor that affect the uniformity and conglutination of fiber. High electrospun volt-age leads to the strong stretch of polymer and curl of single fibers.