CAJ | 학술논문

目的：探讨氨甲环酸在全膝关节置换术中的止血作用。方法选择80例行单侧全膝关节置换术患者，平均分为A、B2组（n=40），A组应用氨甲环酸，B组应用同量生理盐水，观察2组患者失血量、输血情况以及凝血指标变化情况。结果 A组总失血量、显性及隐性失血量均显著低于B组（P＜0.05)；输血量和输血例数A组均显著低于B组（P＜0.05)；2组患者在松止血带时和术后3 h凝血功能没有明显改变。结论应用氨甲环酸能显著减少全膝关节置换术的出血量，缩短康复周期，且安全性较高。
목적：탐토안갑배산재전슬관절치환술중적지혈작용。방법선택80례행단측전슬관절치환술환자，평균분위A、B2조（n=40），A조응용안갑배산，B조응용동량생리염수，관찰2조환자실혈량、수혈정황이급응혈지표변화정황。결과 A조총실혈량、현성급은성실혈량균현저저우B조（P＜0.05)；수혈량화수혈례수A조균현저저우B조（P＜0.05)；2조환자재송지혈대시화술후3 h응혈공능몰유명현개변。결론응용안갑배산능현저감소전슬관절치환술적출혈량，축단강복주기，차안전성교고。
Objective This article aims to explore tranexamic acid on the hemostatic effect of total knee arthroplasty.Methods 80 patients who underwent unilateral TKA was selected,and divided into 2 groups as follows: group A accept Tranexamic acid, group B apply the same amount of saline. Patients blood loss, blood transfusion and blood coagulation index changes were studied.Results In group A total blood loss, dominant and recessive blood loss were signiifcantly lower than that of group B (P<0.05); amount of blood transfusion and transfusion cases in group A were signiifcantly lower than that of group B (P<0.05); 2 groups of patients in the tourniquet and 3 h after coagulation function when there is no obvious change.Conclusion Application of tranexamic acid could signiifcantly reduce the blood loss, shorten the recovery period, and high safety in total knee arthroplasty.