CAJ | 학술논문

目的：分析肥厚型心肌病伴恶性室性心律失常行美托洛尔联合小剂量胺碘酮的临床效果。方法选取本院收治的肥厚型心肌病伴恶性室性心律失常患者随机分成观察组与对照组，对照组予小剂量胺碘酮治疗，观察组在对照组基础上加予美托洛尔治疗，比较两组患者心电图变化与不良反应情况。结果两组治疗后QTmin升高且QTd下降，差异均有统计学意义（P＜0.05）。结论肥厚型心肌病伴恶性室性心律失常行美托洛尔联合小剂量胺碘酮的临床效果显著。
목적：분석비후형심기병반악성실성심률실상행미탁락이연합소제량알전동적림상효과。방법선취본원수치적비후형심기병반악성실성심률실상환자수궤분성관찰조여대조조，대조조여소제량알전동치료，관찰조재대조조기출상가여미탁락이치료，비교량조환자심전도변화여불량반응정황。결과량조치료후QTmin승고차QTd하강，차이균유통계학의의（P＜0.05）。결론비후형심기병반악성실성심률실상행미탁락이연합소제량알전동적림상효과현저。
Objective To analyse the clinical effect of hypertrophic cardiomyopathy associated with malignant ventricular arrhythmia treated <br> by metoprolol combined with small dose of amiodarone. Methods The patients which were suffer from malignant ventricular arrhythmia combined with HCM were divided into observation group and control group randomly. Observation group were treated with metoprolol treatment, the control group were treated with low-dose amiodarone, and compared with their electrocardiogram (ecg) changes and adverse reactions of the two groups’ patients. Results The QTmin rised and QTd fell after treatment, the differences were statistically significant (P<0.05). Conclusion It is remarkable to hypertrophic cardiomyopathy associated with malignant ventricular arrhythmia treated by metoprolol which was in combination with small dose of amiodarone.