CAJ | 학술논문

目的：系统评价芪苈强心胶囊对缺血性心肌病患者生活质量的临床疗效。方法：运用系统评价的方法，全面检索近5年来来自万方数据库的相关文献以及所获文献的参考文献。初步筛选其中随机对照的试验方法纳入研究，对纳入研究逐个进行质量评价，而后对其进行系统评价。结果：共42个研究（111例）符合纳入标准，其中有4个试验对生活质量进行了观测。对其进行系统评价，治疗组的疗效高于对照组，其差异有统计学意义。结论：本研究所纳入试验的方法学质量较低，试验病例数太少，且观察时间过短，且没有对药物的安全性、患者的长期预后及病死率进行深入的研究。因此，进行高质量、大样本、长期随访的随机对照试验非常必要。
목적：계통평개기력강심효낭대결혈성심기병환자생활질량적림상료효。방법：운용계통평개적방법，전면검색근5년래래자만방수거고적상관문헌이급소획문헌적삼고문헌。초보사선기중수궤대조적시험방법납입연구，대납입연구축개진행질량평개，이후대기진행계통평개。결과：공42개연구（111례）부합납입표준，기중유4개시험대생활질량진행료관측。대기진행계통평개，치료조적료효고우대조조，기차이유통계학의의。결론：본연구소납입시험적방법학질량교저，시험병례수태소，차관찰시간과단，차몰유대약물적안전성、환자적장기예후급병사솔진행심입적연구。인차，진행고질량、대양본、장기수방적수궤대조시험비상필요。
Objective:To analyze clinical effects of Qili Qiangxin capsule on life quality of patients with ischemic cardiomyopathy. Methods: Relevant literature and references literature in the past five years were retrieved, and the quality of literatures was analyzed. Results:42 studies met the inclusion criteria, of which there are four tests on life quality were observed. The efficacy of the treatment group was higher than the control;the difference between two groups was statistically significant. Conclusion:Because methodological quality of test was lower, number of tests was too small, and the observation time is too short, and there is no security for the drug, the patient's long-term prognosis and mortality in-depth study, so it’s necessary to carry out high-quality, large-sample, long-term follow-up of randomized controlled trials.