CAJ | 학술논문

目的：对实施维持性血液透析者皮肤瘙痒和微炎症之间的关系进行观察与研究。方法本组中32例维持性血液透析者作为研究对象，按是否伴有皮肤瘙痒，将全部患者分成甲组（伴有皮肤瘙痒）与乙组（未伴有皮肤瘙痒），同时选取同期来我院常规体检的健康者16例作为丙组，然后对三组患者C反应蛋白（CRP）进行观察和比较。结果甲、乙组患者透析后的CRP均高于透析前，且差异有统计学意义（P＜0.05）；甲组患者透析后的CRP高于乙组透析后，且差异有统计学意义（P＜0.05）。结论维持性血液透析可加剧微炎症，而微炎症可能与皮肤瘙痒有关。
목적：대실시유지성혈액투석자피부소양화미염증지간적관계진행관찰여연구。방법본조중32례유지성혈액투석자작위연구대상，안시부반유피부소양，장전부환자분성갑조（반유피부소양）여을조（미반유피부소양），동시선취동기래아원상규체검적건강자16례작위병조，연후대삼조환자C반응단백（CRP）진행관찰화비교。결과갑、을조환자투석후적CRP균고우투석전，차차이유통계학의의（P＜0.05）；갑조환자투석후적CRP고우을조투석후，차차이유통계학의의（P＜0.05）。결론유지성혈액투석가가극미염증，이미염증가능여피부소양유관。
Objective Through the observation and research on the relationship between the implementation of pruritus and micro inflammation. In maintenance hemodialysis. Methods In 32 cases of maintenance hemodialysis patients as the research object, according to whether with skin itching, all patients were divided into group A (with skin itching) and group B (not accompanied by itching). At the same time, we selected 16 healthy person who came to our hospital to get body check as group C. Then we got the C reactive protein (CRP) of the three groups to compare. Results The CRP of group A and B after dialysis was significantly higher than that before, while the difference was significant (P<0.05). The CRP of group A after dialysis were higher than group B, the difference was statistically signiifcant (P<0.05). Conclusion Maintenance hemodialysis could enhance the level of microinflammation, and micro inlfammation may have relationship with pruritus.