CAJ | 학술논문

目的：评价针刺蝶腭神经节治疗中重度变应性鼻炎（allergic rhinitis, AR）患者的临床疗效。方法选取2012年8月－2013年11月同仁医院耳鼻喉科及针灸科42例中重度AR患者为研究对象，按随机数字表法随机分为2组各为21例，治疗组针刺蝶腭神经节，每周针刺1次，共4次。对照组针刺风池、百会、迎香、上星、太阳、曲池及足三里穴，每周3次，连续4周。观察2组患者治疗前及治疗后1周、4周时鼻症状总分量表（total nasal symptoms score, TNSS）、鼻炎伴随症状总分量表（total non-nasal symptom score, TNNSS）的变化，并采用鼻结膜炎生活质量问卷调查量表（rhinoconjunctivitis quality of life questionnaire, RQLQ）评价生活质量。结果治疗后1周，治疗组和对照组TNSS、TNNSS和RQLQ评分[治疗组：5.0（4.0，6.0）分比9.0（7.0，10.0）分、1.0（1.0，1.5）分比3.0（3.0，3.0）分、44.0（35.5，50.0）分比60.0（53.5，75.0）分；对照组：6.0（5.5，8.0）分比10.0（8.5，10.1）分、2.0（2.0，3.0）分比3.00（3.0，3.0）分、50.0（45.5，58.0）分比43.0（27.0，48.0）分]与治疗前比较差异均有统计学意义（P均＜0.01），且2组间TNSS、TNNSS和RQLQ评分差异均有统计学意义（P均＜0.01）。治疗后4周，治疗组TNSS[2.0（1.0，3.0）分比3.0（2.0，4.5）分]、TNNSS[1.0（0.0，1.0）分比2.0（2.0，3.0）分]和RQLQ[24.0（19.0，29.0）分比43.0（27.0，48.5）分]评分比较，差异有统计学意义（P均＜0.01）。结论针刺蝶腭神经节治疗中重度AR可改善患者临床症状，提高生活质量，疗效迅速持久，优于常规针刺疗法。
목적：평개침자접악신경절치료중중도변응성비염（allergic rhinitis, AR）환자적림상료효。방법선취2012년8월－2013년11월동인의원이비후과급침구과42례중중도AR환자위연구대상，안수궤수자표법수궤분위2조각위21례，치료조침자접악신경절，매주침자1차，공4차。대조조침자풍지、백회、영향、상성、태양、곡지급족삼리혈，매주3차，련속4주。관찰2조환자치료전급치료후1주、4주시비증상총분량표（total nasal symptoms score, TNSS）、비염반수증상총분량표（total non-nasal symptom score, TNNSS）적변화，병채용비결막염생활질량문권조사량표（rhinoconjunctivitis quality of life questionnaire, RQLQ）평개생활질량。결과치료후1주，치료조화대조조TNSS、TNNSS화RQLQ평분[치료조：5.0（4.0，6.0）분비9.0（7.0，10.0）분、1.0（1.0，1.5）분비3.0（3.0，3.0）분、44.0（35.5，50.0）분비60.0（53.5，75.0）분；대조조：6.0（5.5，8.0）분비10.0（8.5，10.1）분、2.0（2.0，3.0）분비3.00（3.0，3.0）분、50.0（45.5，58.0）분비43.0（27.0，48.0）분]여치료전비교차이균유통계학의의（P균＜0.01），차2조간TNSS、TNNSS화RQLQ평분차이균유통계학의의（P균＜0.01）。치료후4주，치료조TNSS[2.0（1.0，3.0）분비3.0（2.0，4.5）분]、TNNSS[1.0（0.0，1.0）분비2.0（2.0，3.0）분]화RQLQ[24.0（19.0，29.0）분비43.0（27.0，48.5）분]평분비교，차이유통계학의의（P균＜0.01）。결론침자접악신경절치료중중도AR가개선환자림상증상，제고생활질량，료효신속지구，우우상규침자요법。
Objective To assess the clinical efficacy of acupuncture at the sphenopalatine ganglion for the treatment of patients with moderate to severe allergic rhinitis.Methods 42 cases of moderate to severe allergic rhinitis patients in Otorhinolaryngology clinic of Tongren Hospital between August 2012 to November 2013 were randomized into a treatment group and a control group. The treatment group was treated by acupuncturing sphenopalatine ganglion, once per week, altogether 4 times. The control group was treated by acupuncturingFengchi(GB20),Baihui(GV20),Yingxiang(GV29),Shangxing(GV23),Taiyang(EX-HN5), Quchi(LI11) andZusanli (ST36) was used in the control group, 3 times per week for 4 weeks. The changes of the Total Nasal Symptoms Score (TNSS) and the Total Non-Nasal Symptom Score (TNNSS) were evaluated before and after treatment. The Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) was used to evaluate the quality of life.Results One week after treatment, the scores of TNSS, TNNSS and RQLQ in both groups were significantly improved than before the treatment (treatment group: 5.0[4.0, 6.0]vs. 9.0[7.0, 10.0], 1.0[1.0, 1.5]vs. 3.0[3.0, 3.0], 44.0[35.5, 50.0]vs. 60.0[53.5,75.0]; control group: 6.0[5.5, 8.0]vs. 10.0[8.5, 10.1], 2.0[2.0, 3.0]vs. 3.00[3.0, 3.0], 50.0[45.5, 58.0]vs.43.0[27.0, 48.0]; allP<0.01); the scores of TNSS, TNNSS and RQLQ 1 week after treatment in the treatment group were significantly improved than those in the control group. The scores of TNSS(2.0[1.0, 3.0]vs. 3.0[2.0, 4.5]), TNNSS(1.0[0.0, 1.0]vs.2.0[2.0, 3.0]) and RQLQ(24.0[19.0, 29.0]vs. 43.0[27.0, 48.5])4 week after treatment in the treatment group were significantly improved than those in the control group(allP<0.01).Conclusions Acupuncture at the sphenopalatine ganglion could relieve the symptoms and improve the quality of life in patients with moderate to severe allergic rhinitis, and show more rapid and persistent therapeutic effect. It may be superior to the common acupuncture.