中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
3期
335-339
,共5页
生物材料%骨生物材料%人工虎骨粉%骨质疏松%脊椎压缩性骨折%CT%骨痂生长%骨折愈合
生物材料%骨生物材料%人工虎骨粉%骨質疏鬆%脊椎壓縮性骨摺%CT%骨痂生長%骨摺愈閤
생물재료%골생물재료%인공호골분%골질소송%척추압축성골절%CT%골가생장%골절유합
Subject headings：Spinal Fractures%Osteoporotic Fractures%Fractures,Compression%Bony Calus%Fracture Healing
背景：研究证实微创手术修复骨质疏松性脊椎压缩性骨折效果显著，能撑起椎体恢复高度和硬度，达到解除疼痛、早日活动的目的。但是患者术后长期卧床会导致较多的并发症，预后效果不理想。当前许多中药开始应用于骨质疏松性脊椎压缩性骨折的康复。
<br> 目的：观察人工虎骨粉辅助 CT 引导下骨水泥注入微创修复骨质疏松性脊椎压缩性骨折患者的骨痂生长及骨折愈合情况。
<br> 方法：选取85例骨质疏松性脊椎压缩性骨折患者为研究对象，随机将患者分为两组，观察组43例，对照组42例。观察组及对照组患者分别在CT引导下微创经皮椎体成形治疗的基础上配合服用人工虎骨粉及接骨七厘片，观察两组患者骨痂生长、骨折愈合情况以及疼痛缓解时间。
<br> 结果与结论：观察组术后骨痂生长良好，多为Ⅲ级与Ⅳ级患者；显著优于对照组(P <0.05)。在疼痛缓解时间及骨折愈合时间上，观察组显著短于对照组，差异有显著性意义(P <0.05)。观察组患者的JOA评分优良率显著优于对照组(P <0.05)。提示微创经皮椎体成形联合辅助CT引导下骨水泥注入修复骨质疏松性椎体压缩性骨折效果显著，同时配合服用人工虎骨粉对骨折愈合有很好的促进作用。
揹景：研究證實微創手術脩複骨質疏鬆性脊椎壓縮性骨摺效果顯著，能撐起椎體恢複高度和硬度，達到解除疼痛、早日活動的目的。但是患者術後長期臥床會導緻較多的併髮癥，預後效果不理想。噹前許多中藥開始應用于骨質疏鬆性脊椎壓縮性骨摺的康複。
<br> 目的：觀察人工虎骨粉輔助 CT 引導下骨水泥註入微創脩複骨質疏鬆性脊椎壓縮性骨摺患者的骨痂生長及骨摺愈閤情況。
<br> 方法：選取85例骨質疏鬆性脊椎壓縮性骨摺患者為研究對象，隨機將患者分為兩組，觀察組43例，對照組42例。觀察組及對照組患者分彆在CT引導下微創經皮椎體成形治療的基礎上配閤服用人工虎骨粉及接骨七釐片，觀察兩組患者骨痂生長、骨摺愈閤情況以及疼痛緩解時間。
<br> 結果與結論：觀察組術後骨痂生長良好，多為Ⅲ級與Ⅳ級患者；顯著優于對照組(P <0.05)。在疼痛緩解時間及骨摺愈閤時間上，觀察組顯著短于對照組，差異有顯著性意義(P <0.05)。觀察組患者的JOA評分優良率顯著優于對照組(P <0.05)。提示微創經皮椎體成形聯閤輔助CT引導下骨水泥註入脩複骨質疏鬆性椎體壓縮性骨摺效果顯著，同時配閤服用人工虎骨粉對骨摺愈閤有很好的促進作用。
배경：연구증실미창수술수복골질소송성척추압축성골절효과현저，능탱기추체회복고도화경도，체도해제동통、조일활동적목적。단시환자술후장기와상회도치교다적병발증，예후효과불이상。당전허다중약개시응용우골질소송성척추압축성골절적강복。
<br> 목적：관찰인공호골분보조 CT 인도하골수니주입미창수복골질소송성척추압축성골절환자적골가생장급골절유합정황。
<br> 방법：선취85례골질소송성척추압축성골절환자위연구대상，수궤장환자분위량조，관찰조43례，대조조42례。관찰조급대조조환자분별재CT인도하미창경피추체성형치료적기출상배합복용인공호골분급접골칠전편，관찰량조환자골가생장、골절유합정황이급동통완해시간。
<br> 결과여결론：관찰조술후골가생장량호，다위Ⅲ급여Ⅳ급환자；현저우우대조조(P <0.05)。재동통완해시간급골절유합시간상，관찰조현저단우대조조，차이유현저성의의(P <0.05)。관찰조환자적JOA평분우량솔현저우우대조조(P <0.05)。제시미창경피추체성형연합보조CT인도하골수니주입수복골질소송성추체압축성골절효과현저，동시배합복용인공호골분대골절유합유흔호적촉진작용。
BACKGROUND:Minimaly invasive surgery for osteoporotic vertebral compression fractures obtained apparent effects. This method can support the vertebral height recovered and hardness, relieve the pain, and achieve early activity. However, long-term bed rest after surgery wil induce many complications, and the prognosis wil be not ideal. At present, many Chinese herbs have been used to restore osteoporotic vertebral compression fractures.
<br> OBJECTIVE:To observe calus formation and fracture healing in patients with osteoporotic vertebral compression fractures repaired by CT-guided minimaly invasive surgery with bone cement injection and artificial tiger bone meal.
<br> METHODS:A total of 85 cases of osteoporotic vertebral compression fractures were selected. Patients were randomly divided into observation group (n=43) and control group (n=42). Patients in the observation and control groups respectively received CT-guided minimaly invasive percutaneous vertebroplasty, matching with artificial tiger bone meal andJiegu Qili pil. Calus growth, fracture healing and pain relief time were observed in the two groups.
<br> RESULTS AND CONCLUSION:The calus growth was good in patients of the observation group, mainly grade III and IV, and significantly better than in the control group (P < 0.05). Pain relief time and healing time were significantly shorter in the observation group than in the control group (P < 0.05). The excelent and good rate of Japanese Orthopaedic Association score was significantly better in the observation group than in the control group (P < 0.05). These results suggested that CT-guided minimaly invasive percutaneous vertebroplasty in the combination with bone cement injection for osteoporotic vertebral compression fractures can obtain evident effects. The combined use of artificial tiger bone meal has a good promoting effect on fracture healing.
