CAJ | 학술논문

目的：探讨降钙素原(PCT)检测在脓毒血症导致急性肾损伤(AKI)中的指导意义。方法脓毒血症患者50例作为实验组,再将其分为AKI阳性组(8例)和AKI阴性组(42例),50例健康体检者作为对照组,检测各组人员的PCT、C反应蛋白(CRP)和白细胞(WBC)水平。结果实验组PCT、CRP和WBC结果较对照组均明显增高,差异有统计学意义(P<0.05)；AKI阳性组较AKI阴性组PCT明显增高,差异有统计学意义(P<0.05)；CRP、WBC结果比较差异无统计学意义(P>0.05)。结论脓毒血症导致急性肾损伤患者, PCT浓度比CRP和WBC敏感,可评估由脓毒血症导致急性肾损伤的风险。
목적：탐토강개소원(PCT)검측재농독혈증도치급성신손상(AKI)중적지도의의。방법농독혈증환자50례작위실험조,재장기분위AKI양성조(8례)화AKI음성조(42례),50례건강체검자작위대조조,검측각조인원적PCT、C반응단백(CRP)화백세포(WBC)수평。결과실험조PCT、CRP화WBC결과교대조조균명현증고,차이유통계학의의(P<0.05)；AKI양성조교AKI음성조PCT명현증고,차이유통계학의의(P<0.05)；CRP、WBC결과비교차이무통계학의의(P>0.05)。결론농독혈증도치급성신손상환자, PCT농도비CRP화WBC민감,가평고유농독혈증도치급성신손상적풍험。
Objective To investigate the guidance value of procalcitonin (PCT) detection in septicopyemia induced acute kidney injury (AKI). Methods There were 50 septicopyemia patients as the experimental group, and they were divided into AKI positive group (8 cases) and AKI negative group (42 cases). There were also 50 healthy people as the control group. Detections were made on levels of PCT, C-reactive protein (CRP), and white blood cell (WBC). Results The experimental group had increased levels of PCT, CRP, and WBC than the control group, and the difference had statistical significance (P<0.05). The AKI positive group had more obvious increase than the AKI negative group, and the difference had statistical significance (P<0.05). The difference of CRP and WBC was not statistically significant (P>0.05). Conclusion Concentration of PCT is more sensitive than CRP and WBC in patients of septicopyemia induced acute kidney injury, and that can be used to assess the risk of S-AKI.