国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2015年
4期
458-460
,共3页
幽门螺杆菌%消化道疾病%感染
幽門螺桿菌%消化道疾病%感染
유문라간균%소화도질병%감염
Helicobacter pylori%gastrointestinal diseases%infection
目的：了解扬州地区不同人群中幽门螺杆菌（Hp）感染情况及临床分布特点。方法选取该院的门诊、住院患者及体检者共2917例，利用 Hp 尿素酶抗体检测试剂盒（胶体金法）快速检测三类人群的 Hp 感染情况，并对结果进行统计学分析。结果2917例受试者 Hp 总体检出率为32．9％（959／2917），门诊、住院患者及体检人群的 Hp 检出率分别是33．1％、34．5％和30．0％且男女性别间比较差异均无统计学意义（P ＞0．05）；总体来看，Hp 的检出率随受检者年龄的增加而增高。未成年组（少年及儿童）Hp 检出率最低，为16．0％（285／1529）；青壮年人群居中，Hp 检出率为34．0％（221／650）；中老年人群 Hp 检出率最高，为61．38％（453／758）。研究发现，59．8％的消化道疾病患者 Hp 检测阳性，其中以消化性溃疡（74．4％）和胃癌（70．6％）的 Hp 检出率最高，部分血液病、心脑血管病患者及其他疾病患者也有较高 Hp 的检出率。结论扬州地区 Hp 感染分布随年龄增加而增高，与性别无关。消化道疾病（尤其消化性溃疡与胃癌）患者存在高 Hp 感染率，其他疾病与 Hp 关系不可忽略并有待进一步探索。
目的：瞭解颺州地區不同人群中幽門螺桿菌（Hp）感染情況及臨床分佈特點。方法選取該院的門診、住院患者及體檢者共2917例，利用 Hp 尿素酶抗體檢測試劑盒（膠體金法）快速檢測三類人群的 Hp 感染情況，併對結果進行統計學分析。結果2917例受試者 Hp 總體檢齣率為32．9％（959／2917），門診、住院患者及體檢人群的 Hp 檢齣率分彆是33．1％、34．5％和30．0％且男女性彆間比較差異均無統計學意義（P ＞0．05）；總體來看，Hp 的檢齣率隨受檢者年齡的增加而增高。未成年組（少年及兒童）Hp 檢齣率最低，為16．0％（285／1529）；青壯年人群居中，Hp 檢齣率為34．0％（221／650）；中老年人群 Hp 檢齣率最高，為61．38％（453／758）。研究髮現，59．8％的消化道疾病患者 Hp 檢測暘性，其中以消化性潰瘍（74．4％）和胃癌（70．6％）的 Hp 檢齣率最高，部分血液病、心腦血管病患者及其他疾病患者也有較高 Hp 的檢齣率。結論颺州地區 Hp 感染分佈隨年齡增加而增高，與性彆無關。消化道疾病（尤其消化性潰瘍與胃癌）患者存在高 Hp 感染率，其他疾病與 Hp 關繫不可忽略併有待進一步探索。
목적：료해양주지구불동인군중유문라간균（Hp）감염정황급림상분포특점。방법선취해원적문진、주원환자급체검자공2917례，이용 Hp 뇨소매항체검측시제합（효체금법）쾌속검측삼류인군적 Hp 감염정황，병대결과진행통계학분석。결과2917례수시자 Hp 총체검출솔위32．9％（959／2917），문진、주원환자급체검인군적 Hp 검출솔분별시33．1％、34．5％화30．0％차남녀성별간비교차이균무통계학의의（P ＞0．05）；총체래간，Hp 적검출솔수수검자년령적증가이증고。미성년조（소년급인동）Hp 검출솔최저，위16．0％（285／1529）；청장년인군거중，Hp 검출솔위34．0％（221／650）；중노년인군 Hp 검출솔최고，위61．38％（453／758）。연구발현，59．8％적소화도질병환자 Hp 검측양성，기중이소화성궤양（74．4％）화위암（70．6％）적 Hp 검출솔최고，부분혈액병、심뇌혈관병환자급기타질병환자야유교고 Hp 적검출솔。결론양주지구 Hp 감염분포수년령증가이증고，여성별무관。소화도질병（우기소화성궤양여위암）환자존재고 Hp 감염솔，기타질병여 Hp 관계불가홀략병유대진일보탐색。
Objective To investigate the infection status and distribution characteristic of Helicobacter pylori (Hp)in different groups of population in Yangzhou.Methods 2 917 individuals from outpatients,hospitalized patients,and physical examination pop-ulation were recruited in the study.Serum samples from the subjects were rapidly detected using Helicobacter pylori urease antibody detection kits(Colloidal Gold method).The results were statistically analyzed.Results The totally Hp-detection rate of the 2 917 individuals was 32.9% (959/2 917).The Hp-detection rates of outpatients,hospitalized patients,and physical examination popula-tion were 33.1%,34.5% and 30.0% respectively.There were no significant difference in the positive rates between the male and female individuals(P >0.05).Overall,The Hp-positive rates increased with age.The minors(juveniles and children)had the lowest Hp-positive rate 16.0%(285/1 529);The Hp-positive rate of young adults was 34.0%(221/650),which was at the middle;elderly group had the highest Hp-positive rate 61.38%(453/758).59.8% of the patients diagnosed with gastrointestinal diseases were Hp positive.Among which,patients with peptic ulcer(74.4%)and gastric cancer(70.6%)have the highest detection rates.Some pa-tients with blood diseases,cardiovascular disease and some other diseases were also found with high Hp-detection rates.Conclusion The distribution of the Hp infection in population is positively correlated with age,but not with gender.Gastrointestinal diseases, especially peptic ulcers and gastric cancer,have high Hp infection rates,the relationships of Hp infections with some other diseases cannot be ignored and need to be further explored.
