CAJ | 학술논문

目的：了解孕妇尿路感染病源菌群分布及其主要病原菌的耐药状况。方法收集孕妇产检尿液标本，进行细菌培养分离，采用 VITEK2全自动细菌分析仪进行鉴定，对大肠埃希菌、无乳链球菌进行药敏试验并分析。结果2011年和2012年尿液标本培养阳性率分别为4．4％和3．8％，分离出的病源菌数量均排在前五位的分布为大肠埃希菌、无乳链球菌、粪肠球菌、肺炎克雷伯菌、变形杆菌。2年中，大肠埃希菌对其耐药率持续大于50％的抗菌药物为氨苄西林和派拉西林，产超广谱β-内酰胺酶（ESBLs）的大肠埃希菌检出率2012年较2011年有所降低，无乳链球菌对红霉素和克林霉素的耐药率均大于30％。结论孕妇尿路感染的病原菌中大肠埃希菌所占比例最大，病原菌对常见的抗菌药物均存在不同程度的耐药性。
목적：료해잉부뇨로감염병원균군분포급기주요병원균적내약상황。방법수집잉부산검뇨액표본，진행세균배양분리，채용 VITEK2전자동세균분석의진행감정，대대장애희균、무유련구균진행약민시험병분석。결과2011년화2012년뇨액표본배양양성솔분별위4．4％화3．8％，분리출적병원균수량균배재전오위적분포위대장애희균、무유련구균、분장구균、폐염극뢰백균、변형간균。2년중，대장애희균대기내약솔지속대우50％적항균약물위안변서림화파랍서림，산초엄보β-내선알매（ESBLs）적대장애희균검출솔2012년교2011년유소강저，무유련구균대홍매소화극림매소적내약솔균대우30％。결론잉부뇨로감염적병원균중대장애희균소점비례최대，병원균대상견적항균약물균존재불동정도적내약성。
Objective To investigate the distribution characteristics and drug resistance of pathogens isolated from pregnant woman′s urine samples.Methods The urine samples of pregnant women who underwent prenatal examination were collected and cultured.VITEK2 automatic bacterial analyzer was used to identify the bacteria strains,and Escherichia coli ,Streptococcus agalac-tiae were tested for their drug susceptibility.Results The positive rates of urine culture were 4.4%和 3.8% respectively in 2011 and 2012.The top 5 most isolated strains were Escherichia coli ,S .agalactiae ,Enterococcus faecalis ,K .pneumoniae and Propeus vulgaris .In 2011 and 2012,the resistance rates of Escherichia coli to ampicillin and piperacillin was more than 50%,ESBLs-produ-cing rate in Escherichia coli had decreased in 2012 than 2011,the resistance rates of S.agalactiae to erythromycin and clindamycin were more than 30%.Conclusion Escherichia coli accounted for the largest proportion in the strains isolated from urine samples of pregnant women,The pathogen of urinary tract infection in pregnant women are still mainly Gram-negative bacteria(Escherichia co-li),the main pathogens common antibiotics are varying degrees of resistance,pathogens all display common drug resistance of var-ying degrees.