CAJ | 학술논문

目的：探讨降钙素原（PCT）、C反应蛋白（CRP）、白细胞（WBC）等炎症标志物检测在手足口病患儿临床诊断中的意义。方法分析138例手足口患儿（观察组）和50例健康儿童（对照组）的 PCT、WBC 计数、中性粒细胞计数（NC）、淋巴细胞（Ly）、CRP、免疫球蛋白等常见实验室指标，并进行比较。结果观察组患儿 PCT、CRP、WBC、NC、Ly％、IgM 等水平均高于对照组，差异有统计学意义（P ＜0．05）；IgG、IgA 水平均低于对照组，差异有统计学意义（P ＜0．05）。结论PCT、WBC、NC、Ly、CRP等炎症标志物和免疫球蛋白的检测可为小儿手足口病的诊断提供依据。
목적：탐토강개소원（PCT）、C반응단백（CRP）、백세포（WBC）등염증표지물검측재수족구병환인림상진단중적의의。방법분석138례수족구환인（관찰조）화50례건강인동（대조조）적 PCT、WBC 계수、중 성 립 세 포 계수（NC）、림파세포（Ly）、CRP、면역구단백등상견실험실지표，병진행비교。결과관찰조환인 PCT、CRP、WBC、NC、Ly％、IgM 등수평균고우대조조，차이유통계학의의（P ＜0．05）；IgG、IgA 수평균저우대조조，차이유통계학의의（P ＜0．05）。결론PCT、WBC、NC、Ly、CRP등염증표지물화면역구단백적검측가위소인수족구병적진단제공의거。
Objective To investigate the significance of procalcitonin(PCT),C-reactive protein(CRP),white blood cell(WBC) and other inflammatory markers in the diagnosis of pediatric patients with HFMD.Methods 138 cases of pediatric patients with foot and mouth disease(study group)and 50 cases of healthy children(control group)were recruited in the study.Procalcitonin (PCT),white blood cell(WBC),neutrophil count(NC),lymphocyte count(Ly),immunoglobulins,C-reactive protein and other indi-cators were determined and compared.Results PCT,CRP,WBC,NC,Ly% and IgM levels were higher in study group than those in control group,the differences were all statistically significant(P <0.05 );IgG,IgA levels in control group were lower than that in control group,the differences were statistically significant(P <0.05).Conclusion PCT,WBC,NC,Ly,CRP and IgA,IgG,IgM can provide experimental evidence for diagnosis of children with hand foot and mouth disease.