CAJ | 학술논문

目的：：探讨冠状动脉内应用替罗非班在急性心肌梗死急诊经皮冠状动脉介入治疗( Percutaneous Coronary Interven-tion,PCI)中的临床效果。方法：收集2012年11月~2014年5月于本院治疗的急性心肌梗死的75例患者为研究对象,将其随机分为观察组39例和对照组36例,观察组予PCI后冠状动脉内应用替罗非班治疗,对照组予PCI后静脉内应用替罗非班治疗,然后对2组患者术后心肌再灌注指标、术后1周心功能指标、术后1个月内心脏不良事件进行统计及比较。结果：对比2组术后心肌再灌注指标、心脏不良事件,均P<0.05,存在统计学差异,术后1周心功能指标P>0.05,无统计学意义。结论：冠状动脉内应用替罗非班在急性心肌梗死急诊PCI中的临床效果,明显优于静脉内应用替罗非班,建议在临床上推广应用。
목적：：탐토관상동맥내응용체라비반재급성심기경사급진경피관상동맥개입치료( Percutaneous Coronary Interven-tion,PCI)중적림상효과。방법：수집2012년11월~2014년5월우본원치료적급성심기경사적75례환자위연구대상,장기수궤분위관찰조39례화대조조36례,관찰조여PCI후관상동맥내응용체라비반치료,대조조여PCI후정맥내응용체라비반치료,연후대2조환자술후심기재관주지표、술후1주심공능지표、술후1개월내심장불량사건진행통계급비교。결과：대비2조술후심기재관주지표、심장불량사건,균P<0.05,존재통계학차이,술후1주심공능지표P>0.05,무통계학의의。결론：관상동맥내응용체라비반재급성심기경사급진PCI중적림상효과,명현우우정맥내응용체라비반,건의재림상상추엄응용。
Objective:To investigate clinical effect of the intracoronary application for tirofiban in acute myocardial infarction after percutaneous coronary intervention (PCI). Method: from 2012 November ~2014 year in May,75 cases were collected in the hospital treatment of acute myocardial infarction patients as the research object, then they were randomly divided into observation group of 39 cases and 36 cases in the control group, the observation group for tirofiban treatment with PCI after intracoronary application, control group was given PCI after intravenous application of tirofiban treatment, and 2 groups of patients after myocardial reperfusion index, 1 weeks after the operation, heart function index, after 1 months of statistics and adverse cardiac events. Results:the two groups were compared after mark-er of myocardial reperfusion, cardiac adverse events, all P<0. 05, there was significant difference, 1 weeks after the operation, heart function indexes of P>0. 05, no statistical significance. Conclusion:in the clinical effect,the application of tirofiban in acute myocardial infarction of PCI in the coronary artery, is obviously better than that of intravenous application for tirofiban, recommended in clinical ap-plication.