CAJ | 학술논문

目的：对白细胞计数（WBC）、中性粒细胞百分率（N％）、C 反应蛋白（CRP）和降钙素原（PCT）检测在临床细菌感染中的应用价值进行比较分析。方法随机抽取细菌感染性疾病患者70例和同期收治的非细菌感染性疾病患者81例作为研究对象，对其展开 WBC、N％、CRP 及 PCT 检测，对比分析检测结果。结果与非细菌感染组比较，细菌感染组 WBC、N％、CRP 和PCT 均升高，差异有统计学意义（P ＜0．05）；细菌感染组 WBC、N％、CRP 和 PCT 阳性率明显高于非细菌感染组，差异有统计学意义（P ＜0．05）。细菌感染组组内比较发现，N％、CRP 和 PCT 阳性率明显高于 WBC，差异有统计学意义（P ＜0．05）；CRP 阳性率高于 PCT，差异有统计学意义（P ＜0．05），但非细菌感染组 CRP 阳性率较高，PCT 阳性率较低，提示 CRP 假阳性率较高，特异性低，PCT 假阳性率较低，特异性高。结论WBC、N％、CRP 和 PCT 检测在临床细菌感染中均有较大的临床价值，N％、CRP 和PCT 对细菌感染的诊断要优于 WBC。其中，CRP 更为敏感，但特异性低，而 PCT 特异性高，更适用于细菌感染的诊断。
목적：대백세포계수（WBC）、중성립세포백분솔（N％）、C 반응단백（CRP）화강개소원（PCT）검측재림상세균감염중적응용개치진행비교분석。방법수궤추취세균감염성질병환자70례화동기수치적비세균감염성질병환자81례작위연구대상，대기전개 WBC、N％、CRP 급 PCT 검측，대비분석검측결과。결과여비세균감염조비교，세균감염조 WBC、N％、CRP 화PCT 균승고，차이유통계학의의（P ＜0．05）；세균감염조 WBC、N％、CRP 화 PCT 양성솔명현고우비세균감염조，차이유통계학의의（P ＜0．05）。세균감염조조내비교발현，N％、CRP 화 PCT 양성솔명현고우 WBC，차이유통계학의의（P ＜0．05）；CRP 양성솔고우 PCT，차이유통계학의의（P ＜0．05），단비세균감염조 CRP 양성솔교고，PCT 양성솔교저，제시 CRP 가양성솔교고，특이성저，PCT 가양성솔교저，특이성고。결론WBC、N％、CRP 화 PCT 검측재림상세균감염중균유교대적림상개치，N％、CRP 화PCT 대세균감염적진단요우우 WBC。기중，CRP 경위민감，단특이성저，이 PCT 특이성고，경괄용우세균감염적진단。
Objective To investigate and compare the applications of white blood cell count (WBC),neutrophil percentage (N%),C reactive protein (CRP)and procalcitonin (PCT)in the detection of bacterial infections.Methods Patients were randomly recruited in the study,70 patients with bacterial infection disease were recruited in the study as bacterial infection group,81 patients without bacterial infection were enrolled as no infection group.WBC,N%,CRP and PCT were detected,then comparative analysis of test results performed.Results Compared with no bacterial infection group,WBC,N%,CRP and PCT were increased in bacterial infection group(P <0.05),CRP and PCT increased obviously.The positive rate of WBC,N%,CRP and PCT in bacterial infection group was significantly higher than that of no bacterial infection group(P <0.05).In the bacterial infection group,the positive rate of N%,CRP and PCT was significantly higher than that of WBC(P <0.05),the positive rate of CRP was higher than PCT(P <0.05).But the positive rate of CRP was relatively high,and PCT was low in no bacterial infection group,suggesting that the false positive rate of CRP was higher,while that of PCT was lower,which had higher specificity.Conclusion WBC,N%,CRP and PCT all have clinical value for bacterial infections diagnosis.For the diagnosis of bacterial infections,N%,CRP and PCT is superior to WBC.CRP is more sensitive,but less specific,therefore,PCT with higher specificity was more suitable in the diagnosis of bacterial infections.