中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
3期
45-47
,共3页
急性有机磷农药中毒%血液灌流%疗效
急性有機燐農藥中毒%血液灌流%療效
급성유궤린농약중독%혈액관류%료효
Acute organic phosphorus poisoning%Blood perfusion%Effect
目的：探讨床边血液灌流治疗急性有机磷农药中毒的临床效果。方法选取本院ICU 2011年1月~2014年10月收治的急性有机磷农药中毒患者60例，随机分为实验组和对照组，对照组给予常规治疗，实验组在常规治疗的基础上加用床边血液灌流治疗，比较两组患者的昏迷时间、呼吸机脱机时间、阿托品用量、血清胆碱酯酶(CHE)恢复时间、住院时间以及并发症发生率和治愈率。结果实验组患者昏迷时间、呼吸机脱机时间、CHE恢复时间及住院时间均短于对照组，阿托品用量少于对照组，差异有统计学意义(P<0.05)。实验组并发症发生率为10.0%，低于对照组的30.0%，差异有统计学意义(P<0.05)。实验组治愈率为93.3%，高于对照组的76.7%，差异有统计学意义(P<0.05)。结论在常规阿托品等药物治疗的基础上加用床边血液灌流治疗急性有机磷农药中毒可快速改善患者的临床症状，提高治愈率，降低病死率。
目的：探討床邊血液灌流治療急性有機燐農藥中毒的臨床效果。方法選取本院ICU 2011年1月~2014年10月收治的急性有機燐農藥中毒患者60例，隨機分為實驗組和對照組，對照組給予常規治療，實驗組在常規治療的基礎上加用床邊血液灌流治療，比較兩組患者的昏迷時間、呼吸機脫機時間、阿託品用量、血清膽堿酯酶(CHE)恢複時間、住院時間以及併髮癥髮生率和治愈率。結果實驗組患者昏迷時間、呼吸機脫機時間、CHE恢複時間及住院時間均短于對照組，阿託品用量少于對照組，差異有統計學意義(P<0.05)。實驗組併髮癥髮生率為10.0%，低于對照組的30.0%，差異有統計學意義(P<0.05)。實驗組治愈率為93.3%，高于對照組的76.7%，差異有統計學意義(P<0.05)。結論在常規阿託品等藥物治療的基礎上加用床邊血液灌流治療急性有機燐農藥中毒可快速改善患者的臨床癥狀，提高治愈率，降低病死率。
목적：탐토상변혈액관류치료급성유궤린농약중독적림상효과。방법선취본원ICU 2011년1월~2014년10월수치적급성유궤린농약중독환자60례，수궤분위실험조화대조조，대조조급여상규치료，실험조재상규치료적기출상가용상변혈액관류치료，비교량조환자적혼미시간、호흡궤탈궤시간、아탁품용량、혈청담감지매(CHE)회복시간、주원시간이급병발증발생솔화치유솔。결과실험조환자혼미시간、호흡궤탈궤시간、CHE회복시간급주원시간균단우대조조，아탁품용량소우대조조，차이유통계학의의(P<0.05)。실험조병발증발생솔위10.0%，저우대조조적30.0%，차이유통계학의의(P<0.05)。실험조치유솔위93.3%，고우대조조적76.7%，차이유통계학의의(P<0.05)。결론재상규아탁품등약물치료적기출상가용상변혈액관류치료급성유궤린농약중독가쾌속개선환자적림상증상，제고치유솔，강저병사솔。
Objective To investigate the clinical effect of bedside blood perfusion in the treatment of acute organic phosphorus poisoning. Methods 60 patients with acute organic phosphorus poisoning in ICU of our hospital from Jan-uary 2011 to October 2014 were selected,and were divided into experimental group and control group,30 cases in each group.Regular treatment was provided to the control group,while blood perfusion was added to the experimental group on the basis of regular treatment.The coma time,time of breathing machine weaning,dosage of atropine,recovery time of cholinesterase (CHE),hospital stay and the incidence of complications,the cure rate in both groups was compared. Re-sults The coma time,time of breathing machine weaning,recovery time of cholinesterase (CHE),hospital stay in the ex-perimental group was shorter than that in the control group,dosage of atropine was less than that in the control group, the difference was significant (P<0.05).The incidence of complications in the experimental group was 10.0%,lower than 30.0% in the control group,the difference was significant (P<0.05).The cure rate in the experimental group was 93.3%, higher than 76.7% in the control group,the difference was significant (P<0.05). Conclusion On the basis of regular medication like atropine,added bedside blood perfusion on treating acute organic phosphorus poisoning can quickly im-prove patient’s clinical symptoms,increase the cure rate and decrease fatality rate.
