中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
3期
183-185
,共3页
乙型肝炎防治知识%乙型肝炎疫苗%乙型肝炎免疫球蛋白%乙型肝炎%母婴传播
乙型肝炎防治知識%乙型肝炎疫苗%乙型肝炎免疫毬蛋白%乙型肝炎%母嬰傳播
을형간염방치지식%을형간염역묘%을형간염면역구단백%을형간염%모영전파
Knowledge of hepatitis B prevention%Hep-atitis B vaccine%Hepatitis B immunoglobulin%Hepatitis B%Mother-to-fetus transmission
目的：探讨乙型肝炎疫苗联合乙型肝炎免疫球蛋白(HBIG)阻断乙型肝炎病毒(HBV)母婴传播的效果。方法选择2009年1月~2011年6月本院妇产科收治的116例乙型肝炎表面抗原(HBsAg)阳性的乙型肝炎产妇以及已按照免疫程序注射过HBIG以及乙型肝炎疫苗的年龄为1岁的婴儿作为研究对象,采用自制调查问卷对产妇进行乙型肝炎防治知识调查,检测婴儿血清HBsAg。结果 HBsAg阳性产妇对于乙型肝炎能够通过母婴传播的知晓率较高,认为乙型肝炎疫苗和HBIG可以预防乙型肝炎母婴传播者所占比例为74.14%。受检婴幼儿中,HBsAg检测阳性11例(9.48%),阻断成功率为90.52%。母亲为乙肝大、小三阳所生的婴儿HBsAg阳性率分别为14.71%和2.08%,两者比较差异有统计学意义(P<0.05)；母亲孕期接种和未接种HBIG的婴儿HBsAg阳性率分别为6.58%和15.00%,剖腹产以及顺产的婴儿HBsAg阳性率分别为13.51%和7.59%,人工喂养和母乳喂养的婴儿HBsAg阳性率分别为9.09%和8.54%,以上观察指标比较差异均无统计学意义(P跃0.05)。结论加强HBV感染孕妇的乙型肝炎防治知识健康宣教,并按照免疫程序对新生儿联合接种乙型肝炎疫苗和HBIG,可以有效降低乙型肝炎的母婴传播率。
目的：探討乙型肝炎疫苗聯閤乙型肝炎免疫毬蛋白(HBIG)阻斷乙型肝炎病毒(HBV)母嬰傳播的效果。方法選擇2009年1月~2011年6月本院婦產科收治的116例乙型肝炎錶麵抗原(HBsAg)暘性的乙型肝炎產婦以及已按照免疫程序註射過HBIG以及乙型肝炎疫苗的年齡為1歲的嬰兒作為研究對象,採用自製調查問捲對產婦進行乙型肝炎防治知識調查,檢測嬰兒血清HBsAg。結果 HBsAg暘性產婦對于乙型肝炎能夠通過母嬰傳播的知曉率較高,認為乙型肝炎疫苗和HBIG可以預防乙型肝炎母嬰傳播者所佔比例為74.14%。受檢嬰幼兒中,HBsAg檢測暘性11例(9.48%),阻斷成功率為90.52%。母親為乙肝大、小三暘所生的嬰兒HBsAg暘性率分彆為14.71%和2.08%,兩者比較差異有統計學意義(P<0.05)；母親孕期接種和未接種HBIG的嬰兒HBsAg暘性率分彆為6.58%和15.00%,剖腹產以及順產的嬰兒HBsAg暘性率分彆為13.51%和7.59%,人工餵養和母乳餵養的嬰兒HBsAg暘性率分彆為9.09%和8.54%,以上觀察指標比較差異均無統計學意義(P躍0.05)。結論加彊HBV感染孕婦的乙型肝炎防治知識健康宣教,併按照免疫程序對新生兒聯閤接種乙型肝炎疫苗和HBIG,可以有效降低乙型肝炎的母嬰傳播率。
목적：탐토을형간염역묘연합을형간염면역구단백(HBIG)조단을형간염병독(HBV)모영전파적효과。방법선택2009년1월~2011년6월본원부산과수치적116례을형간염표면항원(HBsAg)양성적을형간염산부이급이안조면역정서주사과HBIG이급을형간염역묘적년령위1세적영인작위연구대상,채용자제조사문권대산부진행을형간염방치지식조사,검측영인혈청HBsAg。결과 HBsAg양성산부대우을형간염능구통과모영전파적지효솔교고,인위을형간염역묘화HBIG가이예방을형간염모영전파자소점비례위74.14%。수검영유인중,HBsAg검측양성11례(9.48%),조단성공솔위90.52%。모친위을간대、소삼양소생적영인HBsAg양성솔분별위14.71%화2.08%,량자비교차이유통계학의의(P<0.05)；모친잉기접충화미접충HBIG적영인HBsAg양성솔분별위6.58%화15.00%,부복산이급순산적영인HBsAg양성솔분별위13.51%화7.59%,인공위양화모유위양적영인HBsAg양성솔분별위9.09%화8.54%,이상관찰지표비교차이균무통계학의의(P약0.05)。결론가강HBV감염잉부적을형간염방치지식건강선교,병안조면역정서대신생인연합접충을형간염역묘화HBIG,가이유효강저을형간염적모영전파솔。
Objective To observe the effect of hepatitis B vaccine combined with hepatitis B immunoglobulin (HBIG) to block mother-to-fetus of hepatitis B virus (HBV). Methods 116 pregnant women of positive hepatitis B surface antigen (HBsAg) and infant injected HBIG and hepatitis B vaccine at the age of 1 years according to the immunization program from January 2009 to June 2011 in our hospital were selected as the research object.The questionnaire investigation of hepatitis B prevention knowledge on maternal was used and infant serum HBsAg was detected. Results The rate of mother-to-fetus of hepatitis B virus in pregnant women of HBsAg positive was higher.There was 74.14% of the people thought that the hepatitis B vaccine and HBIG could prevent mother to child transmission of hepatitis B.The infants tested HBsAg positive in 11 cases,the positive rate of HBsAg was 9.48%,blocking the success rate was 90.52%.The positive rate of babies with mother were 14.71% and 2.08%,there was significant difference between the two groups (P<0.05).The positive rate of maternal infant HBsAg inoculated and non inoculated HBIG was 6.58%and 15%.The positive rate of babies with cesarean section and vaginal delivery was 13.51% and 7.59%.The positive rate of HBsAg of artifi-cial feeding and breast-feeding infants was 9.09% and 8.54%,the above observation indexes of two groups was not sig-nificant (P>0.05). Conclusion To strengthen prevention and control of hepatitis B knowledge health education of preg-nant women infected with HBV,and in accordance with the immunization program on neonatal joint vaccination of hep-atitis B vaccine and HBIG,can effectively reduce the rate of mother-to-fetus transmission of hepatitis B.
