临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2015年
4期
619-622
,共4页
李亚楠%周云芝%张楠%王洪武
李亞楠%週雲芝%張楠%王洪武
리아남%주운지%장남%왕홍무
原发性气管癌%支气管镜%介入治疗%治疗效果
原髮性氣管癌%支氣管鏡%介入治療%治療效果
원발성기관암%지기관경%개입치료%치료효과
primary tracheal carcinoma%bronchoscope%interventional treatment%treatment outcome
目的:总结25例晚期原发性气管癌的临床资料,探讨原发性气管癌支气管镜介入的诊治经验。方法回顾性分析煤炭总医院肿瘤内科自2009年9月-2013年7月收治的经支气管镜检查、病理诊断的25例晚期原发性气管癌的临床资料。结果患者年龄44-77岁,平均年龄(64.5±9.8)岁。病理组织学类型,恶性肿瘤25例,其中原发性气管鳞癌患者15例,原发性气管腺样囊性癌患者10例,无良性肿瘤患者。25例患者临床上均以不同程度的咳嗽、咯血及活动后胸闷、气促、喘鸣为最多见症状。手术治疗加支气管镜介入治疗2例,化学治疗加支气管镜介入治疗3例,放射治疗加支气管镜介入治疗1例,单纯以支气管镜下介入治疗为主19例,治疗后患者咳嗽、咯血及活动后胸闷、气促、喘鸣及生活质量明显好转。结论原发性气管癌少见,早期易被误诊,支气管镜检查及病理诊断为确诊的重要方法。手术治疗是原发性气管肿瘤的主要治疗方式,在不能手术时,放射疗法和化疗疗法是有效的治疗手段,但长期疗效是有限的,而单纯支气管镜介入治疗或联合放疗或化疗等治疗可作为晚期气管癌患者姑息治疗的重要手段。经治疗后患者的咳嗽、咯血及活动后胸闷、气促、喘鸣、气促评分及气道阻塞程度显著改善,能迅速缓解气道梗阻,改善生存期,提高生活质量。
目的:總結25例晚期原髮性氣管癌的臨床資料,探討原髮性氣管癌支氣管鏡介入的診治經驗。方法迴顧性分析煤炭總醫院腫瘤內科自2009年9月-2013年7月收治的經支氣管鏡檢查、病理診斷的25例晚期原髮性氣管癌的臨床資料。結果患者年齡44-77歲,平均年齡(64.5±9.8)歲。病理組織學類型,噁性腫瘤25例,其中原髮性氣管鱗癌患者15例,原髮性氣管腺樣囊性癌患者10例,無良性腫瘤患者。25例患者臨床上均以不同程度的咳嗽、咯血及活動後胸悶、氣促、喘鳴為最多見癥狀。手術治療加支氣管鏡介入治療2例,化學治療加支氣管鏡介入治療3例,放射治療加支氣管鏡介入治療1例,單純以支氣管鏡下介入治療為主19例,治療後患者咳嗽、咯血及活動後胸悶、氣促、喘鳴及生活質量明顯好轉。結論原髮性氣管癌少見,早期易被誤診,支氣管鏡檢查及病理診斷為確診的重要方法。手術治療是原髮性氣管腫瘤的主要治療方式,在不能手術時,放射療法和化療療法是有效的治療手段,但長期療效是有限的,而單純支氣管鏡介入治療或聯閤放療或化療等治療可作為晚期氣管癌患者姑息治療的重要手段。經治療後患者的咳嗽、咯血及活動後胸悶、氣促、喘鳴、氣促評分及氣道阻塞程度顯著改善,能迅速緩解氣道梗阻,改善生存期,提高生活質量。
목적:총결25례만기원발성기관암적림상자료,탐토원발성기관암지기관경개입적진치경험。방법회고성분석매탄총의원종류내과자2009년9월-2013년7월수치적경지기관경검사、병리진단적25례만기원발성기관암적림상자료。결과환자년령44-77세,평균년령(64.5±9.8)세。병리조직학류형,악성종류25례,기중원발성기관린암환자15례,원발성기관선양낭성암환자10례,무량성종류환자。25례환자림상상균이불동정도적해수、각혈급활동후흉민、기촉、천명위최다견증상。수술치료가지기관경개입치료2례,화학치료가지기관경개입치료3례,방사치료가지기관경개입치료1례,단순이지기관경하개입치료위주19례,치료후환자해수、각혈급활동후흉민、기촉、천명급생활질량명현호전。결론원발성기관암소견,조기역피오진,지기관경검사급병리진단위학진적중요방법。수술치료시원발성기관종류적주요치료방식,재불능수술시,방사요법화화료요법시유효적치료수단,단장기료효시유한적,이단순지기관경개입치료혹연합방료혹화료등치료가작위만기기관암환자고식치료적중요수단。경치료후환자적해수、각혈급활동후흉민、기촉、천명、기촉평분급기도조새정도현저개선,능신속완해기도경조,개선생존기,제고생활질량。
Objective To summarize the clinical data of 25 patients with advanced primary tracheal carcino-ma. Methods The clinical data of 25 patients with advanced primary tracheal carcinomal from September 2009 to July 2013 were retrospectively analyzed. Results The patients aged from 44 to 77 years old, with a mean age of (64. 5 ± 9. 8) years old. There were 25 cases of malignant tumors, including 15 cases of primary tracheal squamous cell carcinomas and 10 cases of primary tracheal adenoid cystic carcinoma. Their early clinical symptoms were unspe-cific, such as cough, hemoptysis and activity chest tightness, shortness of breath and wheezing. 2 patients were given surgical therapy plus interventional bronchoscopic treatment, 3 cases received chemotherapy plus interventional bron-choscopic treatment, and 1 case received radiation therapy plus interventional bronchoscopic treatment. The main therapy of 19 cases were interventional bronchoscopic treatment. After treatment, their cough, hemoptysis and activity chest tightness, shortness of breath and wheezing and quality of life were improved significantly. Conclusion Prima-ry tracheal carcinoma is extremely rare, so its early diagnosis is critical. Bronchoscopic examination and pathological diagnosis are the important methods of diagnosis.