中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
3期
65-66,69
,共3页
终末期肾病%动态血压参数%动脉粥样硬化
終末期腎病%動態血壓參數%動脈粥樣硬化
종말기신병%동태혈압삼수%동맥죽양경화
End-stage renal disease%Ambulatory blood pressure%Atherosclerosis
目的：研究终末期肾病患者动态血压参数与动脉粥样硬化的相关性。方法收集本院2011年5~11月未开始血液净化治疗或规律采用血液透析≥3个月且年龄跃18岁的终末期肾病患者97例,根据颈动脉超声检查颈动脉斑块形成和(或)颈动脉内中膜增厚者为动脉粥样硬化组,无明显异常者为对照组。采用二项分类变量Lo-gistic回归分析进行相关性分析。结果两组日间平均舒张压、夜间平均舒张压、24 h平均脉压、日间平均脉压、夜间平均脉压比较,差异有统计学意义(P<0.05)。 Logistic回归分析显示,24 h平均舒张压、夜间平均舒张压、24 h平均脉压及夜间平均脉压与动脉粥样硬化密切相关。结论动态血压参数与动脉粥样硬化相关性良好,可指导临床医生早期干预,解除血压异常对慢性肾病的影响,解除可能引起的动脉粥样硬化风险。
目的：研究終末期腎病患者動態血壓參數與動脈粥樣硬化的相關性。方法收集本院2011年5~11月未開始血液淨化治療或規律採用血液透析≥3箇月且年齡躍18歲的終末期腎病患者97例,根據頸動脈超聲檢查頸動脈斑塊形成和(或)頸動脈內中膜增厚者為動脈粥樣硬化組,無明顯異常者為對照組。採用二項分類變量Lo-gistic迴歸分析進行相關性分析。結果兩組日間平均舒張壓、夜間平均舒張壓、24 h平均脈壓、日間平均脈壓、夜間平均脈壓比較,差異有統計學意義(P<0.05)。 Logistic迴歸分析顯示,24 h平均舒張壓、夜間平均舒張壓、24 h平均脈壓及夜間平均脈壓與動脈粥樣硬化密切相關。結論動態血壓參數與動脈粥樣硬化相關性良好,可指導臨床醫生早期榦預,解除血壓異常對慢性腎病的影響,解除可能引起的動脈粥樣硬化風險。
목적：연구종말기신병환자동태혈압삼수여동맥죽양경화적상관성。방법수집본원2011년5~11월미개시혈액정화치료혹규률채용혈액투석≥3개월차년령약18세적종말기신병환자97례,근거경동맥초성검사경동맥반괴형성화(혹)경동맥내중막증후자위동맥죽양경화조,무명현이상자위대조조。채용이항분류변량Lo-gistic회귀분석진행상관성분석。결과량조일간평균서장압、야간평균서장압、24 h평균맥압、일간평균맥압、야간평균맥압비교,차이유통계학의의(P<0.05)。 Logistic회귀분석현시,24 h평균서장압、야간평균서장압、24 h평균맥압급야간평균맥압여동맥죽양경화밀절상관。결론동태혈압삼수여동맥죽양경화상관성량호,가지도림상의생조기간예,해제혈압이상대만성신병적영향,해제가능인기적동맥죽양경화풍험。
Objective To study the relationship between ambulatory blood pressure and atherosclerosis in patients with end stage renal disease. Methods 97 cases of patients with end stage renal disease in our hospital from May to Novem-ber 2011 were selected,who were not start carrying out blood purification therapy or taken with hemodialysis regularly more than 3 months,and the age were mort than 18 years.According to the carotid artery ultrasound,carotid plaque for-mation and (or) internal carotid artery intima thickening was as atherosclerosis group,no obvious abnormalities was as control group.Logistic regression analysis was used to analyze the correlation. Results Average daytime diastolic blood pressure,diastolic blood pressure at night,24 h average pulse pressure,average daytime pulse pressure,average pulse pressure at night between the two groups had significant (P<0.05).Logistic regression analysis showed that,average 24 h diastolic blood pressure,diastolic blood pressure at night,24 h average pulse pressure,and average pulse pressure at night was was related to atherosclerosis closely. Conclusion There is good relationship between ambulatory blood pres-sure and atherosclerosis,can guide clinicians with early intervention,eliminate the influence of abnormal blood pressure on the lifting of chronic kidney disease,may be caused by atherosclerosis risk.
