CAJ | 학술논문

目的：利用超声设备仪动态地对早产儿脑白质损伤进行定量测量及分析并研究其诊断价值。方法通过应用颅脑超声仪及图像处理软件，对2011年7月至2014年7月在该院儿科住院的120例不同胎龄早产儿[异常组（81例）和对照组（39例）]脑白质分别在产后第7、14、21、28天4个时间段进行不同层面（分别为侧脑室后角旁白质区、侧脑室旁皮质下白质区及半卵圆中心区）平均灰度值测量，研究两组不同时间段、不同层面脑白质灰度值的动态变化，并进行对比研究。结果早产儿产后第7、14、21、28天这4个时间段对照组所测不同层面脑白质平均灰度值均低于相对应同层面异常组水平，差异有统计学意义（P<0.05）；异常组产后第7、14、21、28天4个时间段所测不同层面脑白质平均灰度值前后差值均呈递增趋势。结论超声定量检测能够动态地监测早产儿脑白质损伤的变化情况，对判断脑白质损伤病情程度有重要帮助，能够为临床诊断及调整治疗方案提供依据。
목적：이용초성설비의동태지대조산인뇌백질손상진행정량측량급분석병연구기진단개치。방법통과응용로뇌초성의급도상처리연건，대2011년7월지2014년7월재해원인과주원적120례불동태령조산인[이상조（81례）화대조조（39례）]뇌백질분별재산후제7、14、21、28천4개시간단진행불동층면（분별위측뇌실후각방백질구、측뇌실방피질하백질구급반란원중심구）평균회도치측량，연구량조불동시간단、불동층면뇌백질회도치적동태변화，병진행대비연구。결과조산인산후제7、14、21、28천저4개시간단대조조소측불동층면뇌백질평균회도치균저우상대응동층면이상조수평，차이유통계학의의（P<0.05）；이상조산후제7、14、21、28천4개시간단소측불동층면뇌백질평균회도치전후차치균정체증추세。결론초성정량검측능구동태지감측조산인뇌백질손상적변화정황，대판단뇌백질손상병정정도유중요방조，능구위림상진단급조정치료방안제공의거。
Objective Take advantage of ultrasonic equipment to detect and analyze dynamically quantitative the brain white matter damage in premature infants and study its diagnostic value. Methods The average gray﹣scale values of 120 prema﹣ture infants′s cerebral white matter with different gestational age on the postpartum 7th d ,14th d,the 21th d and 28th d from July 2011 to July 2014 in various layers (the narrator white matter at the posteior horn of lateral ventricle ,subcortical white matter area near the lateral ventricle and half egg circle center ) were measured by craniocerebral ultrasound and image disposal software ,in﹣cluding 81 cases in the abnormal group and 39 cases in the control group. The dynamic variation of gray﹣scale values in the differ﹣ent layers at various times of the two groups were compared and analyzed. Results The premature infants in the control group on the postpartum 7th d,14th d,the 21th d and 28th d were lower than the abnormal group in average gray level values of different﹣plane white matter,the difference was statistically significant(P<0.05);The abnormal group on the postpartum 7th d,14th d,the 21th d and 28th d had an increasing trend in difference of average gray level values of different﹣plane white matter. Conclusion Quantitative ultrasonic detection could dynamically monitor the change of premature white matter lesions and help to judge white matter damage degree of illness,which could provide the basis for clinical diagnosis and treatment.