现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2015年
3期
337-339
,共3页
氯胺酮/治疗应用%七氟醚%儿童%麻醉,全身/方法%外科手术,小/方法%麻醉药,全身
氯胺酮/治療應用%七氟醚%兒童%痳醉,全身/方法%外科手術,小/方法%痳醉藥,全身
록알동/치료응용%칠불미%인동%마취,전신/방법%외과수술,소/방법%마취약,전신
Ketamine/therapeutic use%Sevoflurane%Child%Anesthesia,general/methods%Surgical procedures,minor/methods%Anesthetics,general
目的：观察小剂量氯胺酮复合七氟醚麻醉在小儿短小手术中应用的安全性及可行性。方法选择2012年8月至2014年3月择期行短小手术的患儿80例，将其分成A、B两组，各40例；A组采用七氟醚复合氯胺酮麻醉，B组采用单纯氯胺酮麻醉。麻醉过程中监测两组患儿入室安静后5 min（T1）、麻醉诱导后（T2）、切皮时即刻（T3）、术毕（T4）呼吸循环相关参数，记录不良反应、苏醒时间及氯胺酮用量。结果 A组患儿氯胺酮用量明显少于B组，术后苏醒时间明显短于B组，各种不良反应发生率低于B组，差异均有统计学意义（P<0.05）；B组T2、T3、T4时心率、平均动脉压上升均较A组显著，差异均有统计学意义（P<0.05）。结论小剂量氯胺酮复合七氟醚麻醉用于小儿短小手术比单纯氯胺酮麻醉更平稳，用药更少，苏醒更快，不良反应更少，值得临床推广应用。
目的：觀察小劑量氯胺酮複閤七氟醚痳醉在小兒短小手術中應用的安全性及可行性。方法選擇2012年8月至2014年3月擇期行短小手術的患兒80例，將其分成A、B兩組，各40例；A組採用七氟醚複閤氯胺酮痳醉，B組採用單純氯胺酮痳醉。痳醉過程中鑑測兩組患兒入室安靜後5 min（T1）、痳醉誘導後（T2）、切皮時即刻（T3）、術畢（T4）呼吸循環相關參數，記錄不良反應、囌醒時間及氯胺酮用量。結果 A組患兒氯胺酮用量明顯少于B組，術後囌醒時間明顯短于B組，各種不良反應髮生率低于B組，差異均有統計學意義（P<0.05）；B組T2、T3、T4時心率、平均動脈壓上升均較A組顯著，差異均有統計學意義（P<0.05）。結論小劑量氯胺酮複閤七氟醚痳醉用于小兒短小手術比單純氯胺酮痳醉更平穩，用藥更少，囌醒更快，不良反應更少，值得臨床推廣應用。
목적：관찰소제량록알동복합칠불미마취재소인단소수술중응용적안전성급가행성。방법선택2012년8월지2014년3월택기행단소수술적환인80례，장기분성A、B량조，각40례；A조채용칠불미복합록알동마취，B조채용단순록알동마취。마취과정중감측량조환인입실안정후5 min（T1）、마취유도후（T2）、절피시즉각（T3）、술필（T4）호흡순배상관삼수，기록불량반응、소성시간급록알동용량。결과 A조환인록알동용량명현소우B조，술후소성시간명현단우B조，각충불량반응발생솔저우B조，차이균유통계학의의（P<0.05）；B조T2、T3、T4시심솔、평균동맥압상승균교A조현저，차이균유통계학의의（P<0.05）。결론소제량록알동복합칠불미마취용우소인단소수술비단순록알동마취경평은，용약경소，소성경쾌，불량반응경소，치득림상추엄응용。
Objective To observe safety,feasibility and advantages of of small﹣dose of ketamine combined with sevoflu﹣rane in the application of children′s anesthesia in small operations. Methods A total of 80 children patients with optionally small operations from August 2012 to March 2014 were randomly divided into group A and group B ,each of 40 cases. Group A was given anesthesia with ketamine combined with sevoflurane while group B with ketamine. During the anesthesia ,it was detect﹣ed the related parameters,record adverse reactions,the recovery time and the dosage of ketamine 5 min after being quiet in the operating room (T1),anesthesia induction (T2),the time of skin incision (T3) and completion of the operation. Results Group A was significantly less than group B in ketamine dosage,shorter postoperative recovery time,less in adverse reactions,whose dif ference had statistical significance(P<0.05);heart rate and mean arterial blood pressure at T2,T4,T3 of group B were increased than group A,the difference had statistical significance(P<0.05). Conclusion Smal﹣dose ketamine combined with sevoflurane anesthesia for pediatric short operation than ketamine intravenous anesthesia is more stable with less medication ,faster recovery and less adverse reactions,being worthy to expand in clinic.
