CAJ | 학술논문

目的：探讨肾嗜酸细胞腺瘤的临床病理学特点及诊断要点。方法对我院收治的肾嗜酸细胞腺瘤3例的临床资料、病理形态学及免疫组化结果进行分析,并结合文献对其诊断及鉴别诊断进行探讨。结果本组中肾占位2例,肾上腺占位1例。镜下可见肿瘤细胞排列呈实性巢索状、乳头状或呈腺泡结构,胞质丰富,嗜酸,间质少,伴透明样变性；瘤细胞呈圆形或多角形,细胞核圆形规则,染色质分布均匀,核仁位于中央,核分裂象少见。免疫组化显示CK、EMA表达均阳性,Vimentin、Hale胶体铁表达均阴性。病理诊断肾嗜酸细胞腺瘤。结论肾嗜酸细胞腺瘤较少见,提高对该病的认识,对避免误诊至关重要。
목적：탐토신기산세포선류적림상병이학특점급진단요점。방법대아원수치적신기산세포선류3례적림상자료、병리형태학급면역조화결과진행분석,병결합문헌대기진단급감별진단진행탐토。결과본조중신점위2례,신상선점위1례。경하가견종류세포배렬정실성소색상、유두상혹정선포결구,포질봉부,기산,간질소,반투명양변성；류세포정원형혹다각형,세포핵원형규칙,염색질분포균균,핵인위우중앙,핵분렬상소견。면역조화현시CK、EMA표체균양성,Vimentin、Hale효체철표체균음성。병리진단신기산세포선류。결론신기산세포선류교소견,제고대해병적인식,대피면오진지관중요。
Objective To explore the clinicopathologic characteristics and diagnostic criteria of renal oncocyto-ma. Methods The clinical data, pathomorphology and immunohistochemical staining results of 3 patients with renal on-cocytoma were analyzed, and its diagnosis and differential diagnosis were studied in combination of with the literature. Results Two patients were found to have kidney lesion, and one patient was found to have adrenal mass. Microscopic examination showed that the tumor cells were arranged in the form of solid nest, papillary or acinar structures, and with abundant eosinophilic cytoplasm and less hyaline degeneration in interstitial tissue;the tumor cells were round or polygo-nal, and the cell nucleus was round and regular, chromatin was well distributed, the nucleolus was located centrally, and there were rare mitotic figures. Immunohistochemical staining showed that the expressions of CK and EMA were positive, and the expressions of Vimentin and Hale colloidal iron staining were negative. Pathologic diagnosis was renal oncocyto-ma. Conclusion Renal oncocytoma is rare, and it is essential to avoid misdiagnosis by raising awareness of the disease.