CAJ | 학술논문

目的：观察新辅助化疗治疗Ⅲa期非小细胞肺癌的临床疗效。方法选取本院2006年1月～2009年12月收治的60例Ⅲa期非小细胞肺癌患者为研究对象。直接行手术治疗的患者设为对照组，手术前行新辅助化疗的患者设为观察组，各30例。观察新辅助化疗有效率，两组的并发症发生情况，随访两组术后1年、3年、5年的生存情况，计算两组并发症发生率和术后1年、3年、5年生存率。结果两组并发症发生率、术后1年生存率无显著差异，但术后3年、5年生存率差异具有统计学意义，P＜0.05。结论新辅助化疗治疗Ⅲa期非小细胞肺癌能够延长患者的生存时间，不增加术后并发症发生率。
목적：관찰신보조화료치료Ⅲa기비소세포폐암적림상료효。방법선취본원2006년1월～2009년12월수치적60례Ⅲa기비소세포폐암환자위연구대상。직접행수술치료적환자설위대조조，수술전행신보조화료적환자설위관찰조，각30례。관찰신보조화료유효솔，량조적병발증발생정황，수방량조술후1년、3년、5년적생존정황，계산량조병발증발생솔화술후1년、3년、5년생존솔。결과량조병발증발생솔、술후1년생존솔무현저차이，단술후3년、5년생존솔차이구유통계학의의，P＜0.05。결론신보조화료치료Ⅲa기비소세포폐암능구연장환자적생존시간，불증가술후병발증발생솔。
Objective To observe the clinical efficacy of neoadjuvant chemo- therapy inⅢa stage non-small cell lung cancer.Methods Selected 60 cases withⅢa stage non-small cell lung cancer in our hospital between January 2006 and December 2009, as the research object, and divided into two groups, 30 cases in each group. To observe two groups of postoperative follow-up of 1 year, 3 years, 5 years survival condition, calculation of two groups the incidence of complications and postoperative 1 year, 3 years, 5 years of survival rate.Results Two groups of complications and postoperative 1 year survival rate was no significant difference, but after 3 years, the 5-year survival rate was signiifcantly different,P<0.05. Conclusion Neoadjuvant chemotherapy can effectively extending survival rates ofⅢa stage non-small cell lung cancer patients and don’t raise the post-operative complications.