CAJ | 학술논문

目的：观察并比较自体带蒂颊脂垫瓣( PBFPF)与异种脱细胞真皮基质( ADM )在修复颊黏膜缺损中的临床效果。方法选取颊黏膜病损切除后需修补患者共46例,随机分为PBFPF组和ADM组。观察并记录两组患者术前及术后1~6个月最大开口度( MMO)、手术修复时间等,并结合患者满意度进行统计学分析。结果 PBFPF组术后1~3 d MMO均低于ADM组,差异有统计学意义(P<0．05)；而术后1周至6个月两组MMO相比差异无统计学意义；两者手术修复时间相比,差异有统计学意义( P<0．05)；比较两组患者满意度,差异无统计学意义。结论两种方法均可满足颊部良性肿瘤及口腔中后部T2 N0 M0恶性肿瘤初次的治疗要求,ADM使用更加灵活。但受病例数限制,对于首次切除T2 N0 M0及以下恶性肿瘤首选ADM修复是否合适,还需进一步研究。
목적：관찰병비교자체대체협지점판( PBFPF)여이충탈세포진피기질( ADM )재수복협점막결손중적림상효과。방법선취협점막병손절제후수수보환자공46례,수궤분위PBFPF조화ADM조。관찰병기록량조환자술전급술후1~6개월최대개구도( MMO)、수술수복시간등,병결합환자만의도진행통계학분석。결과 PBFPF조술후1~3 d MMO균저우ADM조,차이유통계학의의(P<0．05)；이술후1주지6개월량조MMO상비차이무통계학의의；량자수술수복시간상비,차이유통계학의의( P<0．05)；비교량조환자만의도,차이무통계학의의。결론량충방법균가만족협부량성종류급구강중후부T2 N0 M0악성종류초차적치료요구,ADM사용경가령활。단수병례수한제,대우수차절제T2 N0 M0급이하악성종류수선ADM수복시부합괄,환수진일보연구。
Objective To observe and compare the clinical effect of PBFPF and ADM on repairing the defect of buccal mucosa. Methods Forty-six patients were randomly divided into two groups( PBFPF and ADM) . The post-operative 1 to 6 months MMO, repaired time and patients’ satisfaction of two groups were observed, recorded and analyzed. Results The MMO was statistically less in the group ADM 1~3 days after surgery (P<0. 05). 1~6 months after surgery, statistically significant difference was not found in MMO between the two groups. The re-paired time between the two groups was statistically different ( P<0. 05 ) . And there was no statistically significant difference in the two groups about satisfaction degree. Conclusion The ADM is more flexible of the two methods that successfully satisfy the need to treat buccal benign tumoers and malignant tumors( T2 N0 M0 ) for the first time. Considering the limited number of samples, further study is required to prove the surgical treatment effect of ADM on repairing the disease( T2 N0 M0 or T1 N0 M0 ) taking primary surgical resection.