CAJ | 학술논문

目的：探讨尼莫地平治疗慢性脑供血不足（CCCI）的疗效。方法将110例CCCI患者随机分为两组，各55例。对照组患者采用常规治疗方法（阿司匹林、胞磷酸胆碱、活血化瘀中成药等），治疗组患者在常规治疗基础上加用尼莫地平口服；观察两组患者的临床疗效及治疗前后经颅多普勒超声（TCD）的变化。结果治疗组患者的临床疗效总有效率为78.2%，明显优于对照组的52.7%，差异有统计学意义（P＜0.01）；两组患者治疗前后TCD比较，治疗组患者的总有效率为76.4%，明显高于对照组的56.4%，差异有统计学意义（P＜0.05）。结论尼莫地平治疗CCCI疗效好，安全方便，且价格低廉。
목적：탐토니막지평치료만성뇌공혈불족（CCCI）적료효。방법장110례CCCI환자수궤분위량조，각55례。대조조환자채용상규치료방법（아사필림、포린산담감、활혈화어중성약등），치료조환자재상규치료기출상가용니막지평구복；관찰량조환자적림상료효급치료전후경로다보륵초성（TCD）적변화。결과치료조환자적림상료효총유효솔위78.2%，명현우우대조조적52.7%，차이유통계학의의（P＜0.01）；량조환자치료전후TCD비교，치료조환자적총유효솔위76.4%，명현고우대조조적56.4%，차이유통계학의의（P＜0.05）。결론니막지평치료CCCI료효호，안전방편，차개격저렴。
Objective To investigate the effect of nimodipine in the treatment of chronic cerebral circulation insuffic- iency.Methods 110 patients were randomly divided into two groups of chronic cerebral circulation insufficiency,55 cases in each.The control group routine treatment methods in patients with(aspirin and celular phosphocholine, promoting blood circulation to remove blood stasis medicine and so on),the patients in the treatment group were added with nimodipine oral on the basis of conventional treatment;to observe the changes of TCD before and after treatment in two groups.Results The clinical curative effect of the patients in the treatment group the total effective rate was 78.2%,significantly better than the control group 52.7%,the difference was statisticaly significant(P<0.01); comparison of TCD before and after treatment in the patients of two groups,with 76.4% patients in the treatment group the total efficiency of 56.4%,significantly higher than the control group,there were statistical significance the difference(P<0.05).Conclusion Nimodipine in the treatment of chronic cerebral circulation insufficiency of good curative effect,safety and convenience,and the price is low.