CAJ | 학술논문

目的：评价奥曲肽在治疗恶性肠梗阻中的疗效。方法：运用计算机检索PubMed，EBSCO，Web of science， VIP，CNKI数据库，收集奥曲肽在治疗恶性肠梗阻相关临床试验，试验都是以随机或半随机对照开展的，并对入选的研究进行Jadad评分和质量评价，运用RevMan5.0对数据进行统计学分析，并对统计结果进行综合评价。结果：共纳入8个研究，共计421例病人。meta分析结果显示：联用奥曲肽的常规治疗的治疗效果均优于常规治疗（各种症状的缓解情况），且差异都有统计学意义。结论：联用奥曲肽在治疗恶性肠梗阻中确实有效，但是纳入的样本较少且质量不是太高，因此我们需要更多更全面的试验样本来提高分析的准确性。
목적：평개오곡태재치료악성장경조중적료효。방법：운용계산궤검색PubMed，EBSCO，Web of science， VIP，CNKI수거고，수집오곡태재치료악성장경조상관림상시험，시험도시이수궤혹반수궤대조개전적，병대입선적연구진행Jadad평분화질량평개，운용RevMan5.0대수거진행통계학분석，병대통계결과진행종합평개。결과：공납입8개연구，공계421례병인。meta분석결과현시：련용오곡태적상규치료적치료효과균우우상규치료（각충증상적완해정황），차차이도유통계학의의。결론：련용오곡태재치료악성장경조중학실유효，단시납입적양본교소차질량불시태고，인차아문수요경다경전면적시험양본래제고분석적준학성。
Objective:To evaluate the efifcacy of octreotide for magligant bowel obstruction.Methods:Databases including Pubmed, EBSCO,Web of science,VIP, and CNKI were searched to find the randomized controlled trials or quasi-randomed controlled trials, which contained the conventional therapy with octreotide versus conventional therapy for maligant bowel obstruction. We made a quality evaluation by Jadad scoring method, and used RevMan 5.0 statistic software to analyze the data in the articles, and then evaluated the results comprehensively. Results: 8 studies (421 patients) were enrolled. The results of meta-analys is showed that there was a significant difference between the ocrteotide with conventional and conventional (efficient of treatment, relief of correlate symptoms). Conclusion: Based on these interrelated results, we can understanding that octretoide had good effective for maligant bowel obstruction, however the samples were not enough and lack of high quality, so we need to elevate the accuracy by getting more studies to the statistical analysis.