CAJ | 학술논문

目的：对普伐他汀导致相关肌病不良反应的最新研究进展进行简要综述，探讨普伐他汀在临床上的合理应用及肌病不良反应的防治措施。方法检索EMbase、万方数据库、中国生物医学文献数据库中相关文献，结合临床，进行综合分析。结果普伐他汀可致相关性肌病、疲倦和劳力性疲劳等不良反应。结论制定普伐他汀的合理用药方案，最大限度地发挥其降脂疗效，减少肌病等不良反应的发生。
목적：대보벌타정도치상관기병불량반응적최신연구진전진행간요종술，탐토보벌타정재림상상적합리응용급기병불량반응적방치조시。방법검색EMbase、만방수거고、중국생물의학문헌수거고중상관문헌，결합림상，진행종합분석。결과보벌타정가치상관성기병、피권화로력성피로등불량반응。결론제정보벌타정적합리용약방안，최대한도지발휘기강지료효，감소기병등불량반응적발생。
Objective To briefly review the latest research progress about adverse reactions of pravastatin re-lated myopathy,investigate the reasonable application of pravastatin in the clinical and prevention measures of myopa-thy adverse reactions. Methods The EMbase,Wanfang database,China biomedical literature database of relevant liter-atures were retrieved,and the results were comprehensively analyzed combined with clinical. Results Pravastatin can cause related myopathy,tired and exertional fatigue and other adverse reactions. Conclusion Rational use of pravasta-tin can maximize its lipid-lowering effect,reduce the occurrence of adverse reactions such as myopathy.