中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
36期
8-10
,共3页
注射抗菌药%药物利用指数%用药分析
註射抗菌藥%藥物利用指數%用藥分析
주사항균약%약물이용지수%용약분석
Injection of antibacterial drug%Drug utilization index%Analysis of drug use
目的：了解该院住院科室注射抗菌药使用情况，探讨临床合理用药。方法收集该院2014年6月1日—30日的8个住院科室应用注射抗菌药有关数据，以限定日剂量（DDD)为单位，计算不同科室抗菌药用药频度（DDDs)和药物利用指数（DUI)并进行分析。结果住院科室注射抗菌药涉及6类21个品种，统属β-内酰胺类的青霉素类、头孢菌素类及非典型β-内酰胺类抗菌药占抗菌药物使用总强度的94.5%，而青霉素类和头孢菌素类复合制剂占抗菌药物使用总强度的41.4%， DDDs排序前5位依次为美洛西林钠舒巴坦钠、头孢地嗪钠、头孢哌酮钠他唑巴坦钠、头孢甲肟和磺苄西林钠；DDD排序前10位的抗菌药中有5个品种DUI值等于或接近2。结论个别住院科室可能存在用药集中、过度用药及单次用药剂量偏大的问题。
目的：瞭解該院住院科室註射抗菌藥使用情況，探討臨床閤理用藥。方法收集該院2014年6月1日—30日的8箇住院科室應用註射抗菌藥有關數據，以限定日劑量（DDD)為單位，計算不同科室抗菌藥用藥頻度（DDDs)和藥物利用指數（DUI)併進行分析。結果住院科室註射抗菌藥涉及6類21箇品種，統屬β-內酰胺類的青黴素類、頭孢菌素類及非典型β-內酰胺類抗菌藥佔抗菌藥物使用總彊度的94.5%，而青黴素類和頭孢菌素類複閤製劑佔抗菌藥物使用總彊度的41.4%， DDDs排序前5位依次為美洛西林鈉舒巴坦鈉、頭孢地嗪鈉、頭孢哌酮鈉他唑巴坦鈉、頭孢甲肟和磺芐西林鈉；DDD排序前10位的抗菌藥中有5箇品種DUI值等于或接近2。結論箇彆住院科室可能存在用藥集中、過度用藥及單次用藥劑量偏大的問題。
목적：료해해원주원과실주사항균약사용정황，탐토림상합리용약。방법수집해원2014년6월1일—30일적8개주원과실응용주사항균약유관수거，이한정일제량（DDD)위단위，계산불동과실항균약용약빈도（DDDs)화약물이용지수（DUI)병진행분석。결과주원과실주사항균약섭급6류21개품충，통속β-내선알류적청매소류、두포균소류급비전형β-내선알류항균약점항균약물사용총강도적94.5%，이청매소류화두포균소류복합제제점항균약물사용총강도적41.4%， DDDs배서전5위의차위미락서림납서파탄납、두포지진납、두포고동납타서파탄납、두포갑우화광변서림납；DDD배서전10위적항균약중유5개품충DUI치등우혹접근2。결론개별주원과실가능존재용약집중、과도용약급단차용약제량편대적문제。
Objective To investigate the use intensity of injection of antibacterial drug in inpatient departments and study the ra-tional clinical drug use. Methods With defined daily dose (DDD) as the unit, the data of injection of antibacterial drug used in 8 inpatient departments of our hospital were collected to calculate and analyze the intensity of Digital Data Display System (DDDs) and drug utilization index (DUI). Results The injection of antibacterial drug in inpatient departments included 6 kinds 21 species, penicillin and cephalosporin belonging to Beta lactam and atypical beta lactam antimicrobials accounted for 94.5% of total antimi-crobial usage intensity, while the penicillin and cephalosporin compound preparation accounted for 41.4%. The first 5 drugs of DDDs were Mezlocillin Sodium and Sulbactam Sodium, Cefodizime Sodium, Cefoperazone Sodium and Tazobactam Sodium, Cef-menoxime and Sulbenicillin Sodium. The DUI of 5 species among the top 10 antibiotics of DDDs was equal or close to 2. Con-clusion Drug concentration, over-medication and an excessive big single dosage were the problems existing in individual inpatient departments.
