中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2015年
1期
27-30
,共4页
周龙%乔甫%黄文治%宗志勇
週龍%喬甫%黃文治%宗誌勇
주룡%교보%황문치%종지용
金黄色葡萄球菌%耐甲氧西林金黄色葡萄球菌%甲氧西林敏感金黄色葡萄球菌%住院时间%预后%医院感染
金黃色葡萄毬菌%耐甲氧西林金黃色葡萄毬菌%甲氧西林敏感金黃色葡萄毬菌%住院時間%預後%醫院感染
금황색포도구균%내갑양서림금황색포도구균%갑양서림민감금황색포도구균%주원시간%예후%의원감염
Staphylococcus aureus%methicillin-resistant Staphylococcus aureus%methicillin-susceptible Staphy-lococcus aureus%length of hospital stay%prognosis%healthcare-associated infection
目的:了解耐甲氧西林金黄色葡萄球菌(MRSA)感染对患者住院时间、院内死亡以及不良预后的影响。方法对2009年1月1日—2013年12月31日华西医院血培养确诊为金黄色葡萄球菌感染的357例住院患者进行回顾性调查分析。结果357例患者,MRSA 感染91例,甲氧西林敏感金黄色葡萄球菌(MSSA)感染266例。MRSA 组和 MSSA 组住院时间比较(29 d vs 23 d),差异有统计学意义(P <0.01);感染前 MRSA 组患者住院时间长于 MSSA 组(P <0.01),感染后两组患者住院时间比较(17 d vs 16.5 d),差异无统计学意义(P =0.92)。MRSA 组和 MSSA 组患者死亡率比较(13.19% vs 9.02%),差异无统计学意义(χ2=1.28,P =0.26);MRSA 组不良预后发生率为29.67%,高于 MSSA 组的16.92%(χ2=6.85,P =0.01)。多因素分析结果显示,MRSA 感染是患者预后不良的独立危险因素(P <0.01)。结论MRSA 感染未增加患者住院时间,但 MRSA 血流感染是患者不良预后的危险因素。
目的:瞭解耐甲氧西林金黃色葡萄毬菌(MRSA)感染對患者住院時間、院內死亡以及不良預後的影響。方法對2009年1月1日—2013年12月31日華西醫院血培養確診為金黃色葡萄毬菌感染的357例住院患者進行迴顧性調查分析。結果357例患者,MRSA 感染91例,甲氧西林敏感金黃色葡萄毬菌(MSSA)感染266例。MRSA 組和 MSSA 組住院時間比較(29 d vs 23 d),差異有統計學意義(P <0.01);感染前 MRSA 組患者住院時間長于 MSSA 組(P <0.01),感染後兩組患者住院時間比較(17 d vs 16.5 d),差異無統計學意義(P =0.92)。MRSA 組和 MSSA 組患者死亡率比較(13.19% vs 9.02%),差異無統計學意義(χ2=1.28,P =0.26);MRSA 組不良預後髮生率為29.67%,高于 MSSA 組的16.92%(χ2=6.85,P =0.01)。多因素分析結果顯示,MRSA 感染是患者預後不良的獨立危險因素(P <0.01)。結論MRSA 感染未增加患者住院時間,但 MRSA 血流感染是患者不良預後的危險因素。
목적:료해내갑양서림금황색포도구균(MRSA)감염대환자주원시간、원내사망이급불량예후적영향。방법대2009년1월1일—2013년12월31일화서의원혈배양학진위금황색포도구균감염적357례주원환자진행회고성조사분석。결과357례환자,MRSA 감염91례,갑양서림민감금황색포도구균(MSSA)감염266례。MRSA 조화 MSSA 조주원시간비교(29 d vs 23 d),차이유통계학의의(P <0.01);감염전 MRSA 조환자주원시간장우 MSSA 조(P <0.01),감염후량조환자주원시간비교(17 d vs 16.5 d),차이무통계학의의(P =0.92)。MRSA 조화 MSSA 조환자사망솔비교(13.19% vs 9.02%),차이무통계학의의(χ2=1.28,P =0.26);MRSA 조불량예후발생솔위29.67%,고우 MSSA 조적16.92%(χ2=6.85,P =0.01)。다인소분석결과현시,MRSA 감염시환자예후불량적독립위험인소(P <0.01)。결론MRSA 감염미증가환자주원시간,단 MRSA 혈류감염시환자불량예후적위험인소。
Objective To understand the impact of methicillin-resistant Staphylococcus aureus (MRSA)blood-stream infection on the length of hospital stay,hospital mortality,and poor prognosis of patients.Methods 357 patients with Staphylococcus aureus (S .aureus)bacteremia in a hospital between January 1 ,2009 and December 31 , 2013 were surveyed and analyzed retrospectively.Results Of 357 patients,91 were infected with MRSA and 266 with methicillin-susceptible S .aureus (MSSA).The length of hospital stay was statistically different between MR-SA and MSSA group(29 d vs 23 d,P <0.01);before infection,length of hospital stay of MRSA group was longer than MSSA group(P <0.01 );after infection,length of hospital stay was not statistically different between two groups(17 d vs 16.5 d,P = 0.92 ).Mortality of MRSA group and MSSA group was not statistically different (13.19% vs 9.02%,χ2 =1 .28,P =0.26).The incidence of poor prognosis of MRSA group was higher than MSSA group(29.67% vs 16.92%,χ2 =6.85,P =0.01 ).Multivariate analysis results showed that MRSA infection was independent risk factor for poor prognosis (P <0.01).Conclusion MRSA infection doesn’t contribute to the pro-longation of hospital stay,but MRSA bloodstream infection is a risk factor for poor prognosis of patients.