CAJ | 학술논문

目的：对某院内科及儿科抗菌药物临床应用情况进行干预，评价其干预效果。方法随机抽取该院内科及儿科2010年7月—12月1880份病例作为对照组（干预前），2011年7月—12月2207份病例作为实验组（干预后），比较两组患者抗菌药物使用情况。结果干预后各科室总抗菌药物使用率为48．12％，低于干预前的58．62％，差异有统计学意义（χ2＝44．45，P ＜0．001）。除内分泌科、儿科、血液科外，其余各科室干预后抗菌药物使用率均明显低于干预前（均 P ＜0．05）。干预前后内分泌科、血液科抗菌药物使用率均不高（＜40％），符合卫生部相关要求。结论通过对抗菌药物临床应用的综合干预，降低了该院内科及儿科抗菌药物使用率。
목적：대모원내과급인과항균약물림상응용정황진행간예，평개기간예효과。방법수궤추취해원내과급인과2010년7월—12월1880빈병례작위대조조（간예전），2011년7월—12월2207빈병례작위실험조（간예후），비교량조환자항균약물사용정황。결과간예후각과실총항균약물사용솔위48．12％，저우간예전적58．62％，차이유통계학의의（χ2＝44．45，P ＜0．001）。제내분비과、인과、혈액과외，기여각과실간예후항균약물사용솔균명현저우간예전（균 P ＜0．05）。간예전후내분비과、혈액과항균약물사용솔균불고（＜40％），부합위생부상관요구。결론통과대항균약물림상응용적종합간예，강저료해원내과급인과항균약물사용솔。
Objective To explore intervention efficacy of clinical application of antimicrobial agents in internal medicine departments of a hospital.Methods 1 880 medical records from internal medicine and pediatrics departments this hospital in July-December 2010 were randomly selected as control group (before intervention),and 2 207 medical records in July-December 2011 were as trial group (after intervention),antimicrobial use of two groups was compared.Results The over-all usage rate of antimicrobial agents after intervention was lower than before intervention (48.12% vs 58.62%,χ2 =44. 45,P <0.001).Except endocrinology,pediatrics and hematology departments,the usage rates of antimicrobial agents in the other departments after intervention were all obviously lower than before intervention(all P <0.05).The usage rate of antimicrobial agents in endocrinology and hematology departments were both low(<40%),which met the requirements of Ministry of Health.Conclusion Comprehensive intervention in clinical use of antimicrobial agents reduced the usage rate of antimicrobial agents in internal medicine and pediatrics departments in this hospital.