CAJ | 학술논문

目的：了解患者经皮肾镜碎石取石术后并发感染的危险因素，为预防患者术后感染提供依据。方法选择2010年8月—2013年8月某院住院行经皮肾镜碎石取石术患者96例，对其临床资料进行回顾性分析，对患者术后感染情况、危险因素及分离病原体等进行分析。结果经皮肾镜碎石取石术后，发生感染35例，感染率为36．46％（35／96）。单因素分析结果显示，结石大小、形状、手术时间以及灌注量是患者术后感染的危险因素（均 P ＜0．05）。对术前96例患者和术后18例患者进行尿细菌培养，共检出病原菌39株，其中大肠埃希菌占首位（12株），其次为铜绿假单胞菌（8株）、草绿色链球菌（5株）、肺炎克雷伯菌（4株）和阴沟肠杆菌（3株）等。结论经皮肾镜取石术后并发感染率高；进行此类手术时，应做好充足地术前准备，有效减少手术时间和术中灌注量；同时，合理使用抗菌药物，以改善患者术后感染情况。
목적：료해환자경피신경쇄석취석술후병발감염적위험인소，위예방환자술후감염제공의거。방법선택2010년8월—2013년8월모원주원행경피신경쇄석취석술환자96례，대기림상자료진행회고성분석，대환자술후감염정황、위험인소급분리병원체등진행분석。결과경피신경쇄석취석술후，발생감염35례，감염솔위36．46％（35／96）。단인소분석결과현시，결석대소、형상、수술시간이급관주량시환자술후감염적위험인소（균 P ＜0．05）。대술전96례환자화술후18례환자진행뇨세균배양，공검출병원균39주，기중대장애희균점수위（12주），기차위동록가단포균（8주）、초록색련구균（5주）、폐염극뢰백균（4주）화음구장간균（3주）등。결론경피신경취석술후병발감염솔고；진행차류수술시，응주호충족지술전준비，유효감소수술시간화술중관주량；동시，합리사용항균약물，이개선환자술후감염정황。
Objective To explore the risk factors for infection following percutaneous nephrolithotomy(PCNL), and provide the basis for prevention of postoperative infection.Methods 96 patients who were performed PCNL in a hospital between August 2010 and August 2013 were chosen,clinical data of patients were retrospectively analyzed, the occurrence of postoperative infection,risk factors and isolated pathogens were analyzed.Results 35 patients (36.46%[35/96])developed infection following PCNL.Univariate analysis revealed that risk factors for postopera-tive infection were the size and shape of stone,duration of operation,and intraoperative perfusion (all P <0.05). 96 patients before operation and 18 patients after operation were performed bacterial culture for urine,a total of 39 strains were isolated,the main isolated pathogens was Escherichia coli (n=12),followed by Pseudomonas aerugi-nosa (n=8),Streptococcus viridans (n =5 ),Klebsiella pneumoniae (n =4)and Enterobacter cloacae (n =3 ). Conclusion Infection rate following PCNL is high,duration of operation and intraoperative perfusion should be re-duced,antimicrobial agents should be used rationally.