CAJ | 학술논문

目的：探讨血浆中降钙素原（PCT）、C-反应蛋白（CRP）水平检测在指导小儿呼吸道感染合理抗生素的临床价值。方法：选取2009年6月至2013年7月我院确诊治疗的呼吸道感染患儿98例，依据随机分配原则分为指导组和对照组，对照组患儿给予常规抗生素治疗，指导组患儿给予PCT、CRP指导下抗生素治疗，统计分析两组患儿临床症状消失、抗生素使用情况和住院时间。结果：指导组患儿咳痰咳嗽、发热、气喘、肺部干湿性啰音症状消失时间与对照组无明显差异，差异无统计学意义（P＞0.05）；指导组患儿抗生素使用率、使用时间和住院时间明显低于对照组，差异无统计学意义（P＜0.05）。结论：PCT、CRP指导下抗生素治疗不影响呼吸道感染患儿疗效，提高治疗过程中抗生素的合理应用。
목적：탐토혈장중강개소원（PCT）、C-반응단백（CRP）수평검측재지도소인호흡도감염합리항생소적림상개치。방법：선취2009년6월지2013년7월아원학진치료적호흡도감염환인98례，의거수궤분배원칙분위지도조화대조조，대조조환인급여상규항생소치료，지도조환인급여PCT、CRP지도하항생소치료，통계분석량조환인림상증상소실、항생소사용정황화주원시간。결과：지도조환인해담해수、발열、기천、폐부간습성라음증상소실시간여대조조무명현차이，차이무통계학의의（P＞0.05）；지도조환인항생소사용솔、사용시간화주원시간명현저우대조조，차이무통계학의의（P＜0.05）。결론：PCT、CRP지도하항생소치료불영향호흡도감염환인료효，제고치료과정중항생소적합리응용。
Objective: To discuss the clinical value of plasma calcitonin (PCT), C-reactive protein (CRP) level testing to guide the rational antibiotics in pediatric respiratory infections.Methods:98 children with respiratory infections were selected in our hospitals,according to the random distribution, all patients were divided into guide group,control group, the control group given conventional antibiotics,guide group given antibiotic treatment under the guidance of PCT,CRP, analysis of two groups clinical symptoms,the usage of antibiotics.Results:Guide group cough phlegm cough,fever,asthma,lung wet sex then symptoms disappear time had no obvious difference with control group(P>0.05);Guide group antibiotics usage,using time,hospitalization time was lower than control group(P<0.05).Conclusion:Under the guidance of PCT,CRP antibiotic treatment does not affect children with respiratory tract infection curative effect,the reasonable application of antibiotics in the process of treatment.