中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2015年
1期
3-4,6
,共3页
超声心动图%心外膜脂肪组织%冠心病
超聲心動圖%心外膜脂肪組織%冠心病
초성심동도%심외막지방조직%관심병
Echocardiography%Epicardial adipose tissue%Coronary heart disease
目的:研究冠心病(coronary heart disease,CHD)患者心外膜脂肪组织(epicardial adipose tissue,EAT)的超声心动图表现,分析其对冠心病的诊断价值。方法:选取2012年12月至2013年4月期间于青岛大学附属医院心内科住院的CHD患者53例作为CHD组,选取同期体检中心健康人员40例作为正常组,所有受试者均接受超声EAT测量和冠状动脉造影检查,统计所有患者超声测量的右心室前壁舒张末期、收缩末期EAT厚度,应用ROC曲线分析法分析其对CHD的诊断价值。结果:CHD组患者右心室前壁舒张、收缩末期EAT厚度明显高于正常组,差异有统计学意义(P<0.05);CHD组患者右心室前壁收缩末期心外膜脂肪组织增厚程度明显高于舒张末期,差异有统计学意义(P<0.05);以EAT厚度>4.5mm诊断CHD,在舒张末期时,敏感度为93.26%,特异度为73.21%,ROC曲线下面积为0.736,在收缩末期时,敏感度为96.53%,特异度为79.49%,ROC曲线下面积为0.872。结论:CHD患者右心室前壁舒张、收缩末期EAT明显增厚,收缩末期EAT增厚程度更为显著,超声测量收缩末期EAT厚度可作为检查冠心病新的诊断指标。
目的:研究冠心病(coronary heart disease,CHD)患者心外膜脂肪組織(epicardial adipose tissue,EAT)的超聲心動圖錶現,分析其對冠心病的診斷價值。方法:選取2012年12月至2013年4月期間于青島大學附屬醫院心內科住院的CHD患者53例作為CHD組,選取同期體檢中心健康人員40例作為正常組,所有受試者均接受超聲EAT測量和冠狀動脈造影檢查,統計所有患者超聲測量的右心室前壁舒張末期、收縮末期EAT厚度,應用ROC麯線分析法分析其對CHD的診斷價值。結果:CHD組患者右心室前壁舒張、收縮末期EAT厚度明顯高于正常組,差異有統計學意義(P<0.05);CHD組患者右心室前壁收縮末期心外膜脂肪組織增厚程度明顯高于舒張末期,差異有統計學意義(P<0.05);以EAT厚度>4.5mm診斷CHD,在舒張末期時,敏感度為93.26%,特異度為73.21%,ROC麯線下麵積為0.736,在收縮末期時,敏感度為96.53%,特異度為79.49%,ROC麯線下麵積為0.872。結論:CHD患者右心室前壁舒張、收縮末期EAT明顯增厚,收縮末期EAT增厚程度更為顯著,超聲測量收縮末期EAT厚度可作為檢查冠心病新的診斷指標。
목적:연구관심병(coronary heart disease,CHD)환자심외막지방조직(epicardial adipose tissue,EAT)적초성심동도표현,분석기대관심병적진단개치。방법:선취2012년12월지2013년4월기간우청도대학부속의원심내과주원적CHD환자53례작위CHD조,선취동기체검중심건강인원40례작위정상조,소유수시자균접수초성EAT측량화관상동맥조영검사,통계소유환자초성측량적우심실전벽서장말기、수축말기EAT후도,응용ROC곡선분석법분석기대CHD적진단개치。결과:CHD조환자우심실전벽서장、수축말기EAT후도명현고우정상조,차이유통계학의의(P<0.05);CHD조환자우심실전벽수축말기심외막지방조직증후정도명현고우서장말기,차이유통계학의의(P<0.05);이EAT후도>4.5mm진단CHD,재서장말기시,민감도위93.26%,특이도위73.21%,ROC곡선하면적위0.736,재수축말기시,민감도위96.53%,특이도위79.49%,ROC곡선하면적위0.872。결론:CHD환자우심실전벽서장、수축말기EAT명현증후,수축말기EAT증후정도경위현저,초성측량수축말기EAT후도가작위검사관심병신적진단지표。
Objective: To study the echocardiographic features of epicardial adipose tissue (EAT) in patients with coronary heart disease(CHD) and analysis the diagnostic value for CHD.Methods:There were total 93 patients,53 of CHD group and 40 of normal control (NC) group. All patients were evaluated by transthoracic echocardiography with measurement of EAT thickness in the anterior wall of right ventricle of heart both at end-systole and end-diastole phase.Results:EAT thickness was significantly different between CHD group and NC group(P<0.05).EAT thickness of the anterior wall of right ventricle increased more at end-systole than that at end-diastole phase(P<0.05).EAT thickness>4.5mm showed 93.26% sensitivity and 73.21% specificity. ROC area 0.736, at end-diastole phase. The same cut-off value showed 96.53% sensitivity and 79.49% specificity, ROC area 0.872, at end-systole phase.Conclusion:EAT thickness of the anterior wall of right ventricle measured by transthoracic echocardiography at end-systole phase may serve as a new diagnostic diameter for coronary heart disease.