中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2015年
1期
80-81
,共2页
NSCLC%三维适形%放疗%不良反应%生活质量%免疫功能
NSCLC%三維適形%放療%不良反應%生活質量%免疫功能
NSCLC%삼유괄형%방료%불량반응%생활질량%면역공능
NSCLC%Three dimensional conformal radiotherapy%Radiotherapy%Adverse reaction%Quality of life%Immune function
目的：探讨益气养阴中药对三维适形放疗局部晚期非小细胞肺癌（NSCLC）老年患者生活质量及免疫功能的影响。方法：回顾性分析我院2010年1月～2013年12月收治的76例NSCLC患者的临床资料，随机分组，对照组采取三维适形放疗，研究组在对照组的基础上采用益气养阴中药治疗。结果：总有效率方面，研究组明显比对照组更优，差异有显著性（P＜0.05）。研究组不良反应均显著低于对照组，差异有显著性（P＜0.05），研究组生活质量评分提高优于对照组，差异也有显著性（P＜0.05），放疗前、后研究组CD8，CD4/CD8比较差异有统计学意义（P＜0.05），放疗前、后研究组中性粒细胞比较差异无统计学意义（P＞0.05）；治疗后，研究组CD8，CD4/CD8及中性粒细胞显著高于对照组，差异有统计学意义（P＜0.05）。结论：益气养阴中药在老年局部晚期非小细胞肺癌方面，通过联合三维适形放疗能够对疾病产生积极影响，降低不良反应，改善免疫功能，提高其生活质量。
目的：探討益氣養陰中藥對三維適形放療跼部晚期非小細胞肺癌（NSCLC）老年患者生活質量及免疫功能的影響。方法：迴顧性分析我院2010年1月～2013年12月收治的76例NSCLC患者的臨床資料，隨機分組，對照組採取三維適形放療，研究組在對照組的基礎上採用益氣養陰中藥治療。結果：總有效率方麵，研究組明顯比對照組更優，差異有顯著性（P＜0.05）。研究組不良反應均顯著低于對照組，差異有顯著性（P＜0.05），研究組生活質量評分提高優于對照組，差異也有顯著性（P＜0.05），放療前、後研究組CD8，CD4/CD8比較差異有統計學意義（P＜0.05），放療前、後研究組中性粒細胞比較差異無統計學意義（P＞0.05）；治療後，研究組CD8，CD4/CD8及中性粒細胞顯著高于對照組，差異有統計學意義（P＜0.05）。結論：益氣養陰中藥在老年跼部晚期非小細胞肺癌方麵，通過聯閤三維適形放療能夠對疾病產生積極影響，降低不良反應，改善免疫功能，提高其生活質量。
목적：탐토익기양음중약대삼유괄형방료국부만기비소세포폐암（NSCLC）노년환자생활질량급면역공능적영향。방법：회고성분석아원2010년1월～2013년12월수치적76례NSCLC환자적림상자료，수궤분조，대조조채취삼유괄형방료，연구조재대조조적기출상채용익기양음중약치료。결과：총유효솔방면，연구조명현비대조조경우，차이유현저성（P＜0.05）。연구조불량반응균현저저우대조조，차이유현저성（P＜0.05），연구조생활질량평분제고우우대조조，차이야유현저성（P＜0.05），방료전、후연구조CD8，CD4/CD8비교차이유통계학의의（P＜0.05），방료전、후연구조중성립세포비교차이무통계학의의（P＞0.05）；치료후，연구조CD8，CD4/CD8급중성립세포현저고우대조조，차이유통계학의의（P＜0.05）。결론：익기양음중약재노년국부만기비소세포폐암방면，통과연합삼유괄형방료능구대질병산생적겁영향，강저불량반응，개선면역공능，제고기생활질량。
Objective: To investigate the effects of Yiqiyangy TCM on the life quality of and immune function in elderly patients with locally advanced non-small cell lung cancer through 3-D conformal radiotherapy.Methods:Retrospective analysis of our hospital in 2010 January to the clinical data of 76 cases of NSCLC patients,in 2013 December were randomized,control group adopted three-dimensional conformal radiotherapy, the research group in the control group based on the use of Yiqiyangy TCM treatment.Results:The total efficiency, the study group was significantly better than the control group, the difference was significant (P<0.05).Study on the adverse reactions were significantly lower than those in control group(P<0.05),quality of life score improved study group than the control group, there were significant differences (P<0.05),CD8 of the study group before and after the treatment, CD4/CD8 had statistical significance difference (P<0.05), the study group neutrophil difference no statistical significance before and after radiotherapy (P>0.05); after the treatment, the study group CD8, CD4/CD8 and neutrophils were significantly higher than the control group, the difference between the two group was statistically significant (P<0.05).Conclusion: Yiqiyangy TCM in elderly patients with locally advanced non small cell lung cancer,through a combination of three dimensional conformal radiotherapy can have a positive impact on the disease, reduce the adverse reactions, improve immune function, improve the quality of life.
