CAJ | 학술논문

目的：探讨出血性脑卒中和缺血性脑卒中患者血清中胶原纤维酸性蛋白(glial fibrillary acidic protein,GFAP)的表达以及对预后的影响°方法用ELISA方法检测出血性脑卒中和缺血性脑卒中患者和健康对照组外周中GFAP的表达水平,统计分析GFAP表达与脑卒中的进展及预后的关系°结果出血性脑卒中患者外周血GFAP表达水平显著高于缺血性脑卒中患者和正常对照组,差异有统计学意义(P<0.05)°结论出血性脑卒中患者外周血GFAP表达水平高于缺血性脑卒中患者和正常对照组,且预后更差°
목적：탐토출혈성뇌졸중화결혈성뇌졸중환자혈청중효원섬유산성단백(glial fibrillary acidic protein,GFAP)적표체이급대예후적영향°방법용ELISA방법검측출혈성뇌졸중화결혈성뇌졸중환자화건강대조조외주중GFAP적표체수평,통계분석GFAP표체여뇌졸중적진전급예후적관계°결과출혈성뇌졸중환자외주혈GFAP표체수평현저고우결혈성뇌졸중환자화정상대조조,차이유통계학의의(P<0.05)°결론출혈성뇌졸중환자외주혈GFAP표체수평고우결혈성뇌졸중환자화정상대조조,차예후경차°
Objective To investigate the expression of glial fibrillary acidic protein (GFAP) in serum of hemorrhagic stroke patients and ischaemic stroke patients and its effects on the prognosis. Methods ELISA test was used to detect the expression of GFAP in peripheral blood of patients with hemorrhagic stroke, patients with ischaemic stroke and healthy controls. And the correlation of GFAP expression with the progress and prognosis of stroke was analyzed statistically. Results The expression of GFAP in the pe_ripheral blood of patients with hemorrhagic stroke was significantly higher than that of patients with ischaemic stroke and the nor_mal control group, there was statistically significant differences between the three groups (P<0.05). Conclusion The expression of GFAP in the peripheral blood of patients with hemorrhagic stroke is much higher than that of the other groups, and makes the prognosis worse.