中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
31期
25-26
,共2页
康艾注射液%化疗%老年肺癌%临床疗效%不良反应
康艾註射液%化療%老年肺癌%臨床療效%不良反應
강애주사액%화료%노년폐암%림상료효%불량반응
Kang'ai injection%Chemotherapy%Elderly lung cancer%Clinical efficacy%Adverse reactions
目的：探讨康艾注射液联合化疗治疗老年肺癌临床疗效及不良反应发生情况。方法选取2013年1-12月收治的90例老年肺癌患者，随机分为两组，观察组和对照组，每组各45例。对照组患者采用单一化疗治疗，观察组患者联合应用化疗和康艾注射液，比较两组患者治疗2个月后的临床疗效和不良反应发生率。结果观察组治疗2个月后疾病控制率95.6%（43/45)，对照组为82.2%（37/45)，差异有统计学意义（P<0.01)；两组患者在客观缓解率差异无统计学意义（P>0.05)；观察组总稳定率（88.9%)明显高于对照组（60%)，差异有统计学意义（P<0.05)；观察组共出现20例不良反应，对照组出现43例，差异有统计学意义（P<0.05)。结论应用康艾注射液联合化疗治疗老年肺癌有助于提高临床疗效，有效控制疾病的稳定性，改善患者的生活质量，减少不良反应的发生，值得在临床上进一步推广。
目的：探討康艾註射液聯閤化療治療老年肺癌臨床療效及不良反應髮生情況。方法選取2013年1-12月收治的90例老年肺癌患者，隨機分為兩組，觀察組和對照組，每組各45例。對照組患者採用單一化療治療，觀察組患者聯閤應用化療和康艾註射液，比較兩組患者治療2箇月後的臨床療效和不良反應髮生率。結果觀察組治療2箇月後疾病控製率95.6%（43/45)，對照組為82.2%（37/45)，差異有統計學意義（P<0.01)；兩組患者在客觀緩解率差異無統計學意義（P>0.05)；觀察組總穩定率（88.9%)明顯高于對照組（60%)，差異有統計學意義（P<0.05)；觀察組共齣現20例不良反應，對照組齣現43例，差異有統計學意義（P<0.05)。結論應用康艾註射液聯閤化療治療老年肺癌有助于提高臨床療效，有效控製疾病的穩定性，改善患者的生活質量，減少不良反應的髮生，值得在臨床上進一步推廣。
목적：탐토강애주사액연합화료치료노년폐암림상료효급불량반응발생정황。방법선취2013년1-12월수치적90례노년폐암환자，수궤분위량조，관찰조화대조조，매조각45례。대조조환자채용단일화료치료，관찰조환자연합응용화료화강애주사액，비교량조환자치료2개월후적림상료효화불량반응발생솔。결과관찰조치료2개월후질병공제솔95.6%（43/45)，대조조위82.2%（37/45)，차이유통계학의의（P<0.01)；량조환자재객관완해솔차이무통계학의의（P>0.05)；관찰조총은정솔（88.9%)명현고우대조조（60%)，차이유통계학의의（P<0.05)；관찰조공출현20례불량반응，대조조출현43례，차이유통계학의의（P<0.05)。결론응용강애주사액연합화료치료노년폐암유조우제고림상료효，유효공제질병적은정성，개선환자적생활질량，감소불량반응적발생，치득재림상상진일보추엄。
Objective To investigate the clinical efficacy and adverse reactions of Kang'ai injection combined with chemotherapy in the treatment of lung cancer in the elderly patients. Methods 90 elderly patients with lung cancer admitted from January 2013 to December 2013 were selected and randomly divided into two groups, the observation group and the control group with 45 pa-tients in each. Patients in the control group were treated by chemotherapy alone, and patients in the observation group were treated by chemotherapy combined with Kang'ai injection. After 2 months of treatment, the clinical efficacy and incidence of adverse re-actions were compared between the two groups. Results After 2 months of treatment, the disease control rate of the observation group was 95.6%(43/45), and that of the control group was 82.2%(37/45) with significant difference (P<0.01);the difference in ob-jective remission rate between the two groups was not statistically significant (P>0.05);the total stable rate of the observation group (88.9%) was significantly higher than that of the control group (60%), the difference was statistically significant (P<0.05); adverse reactions occurred in 20 cases in the observation group, 43 cases in the control group, the difference between the groups was sig-nificant(P<0.05). Conclusion Kang'ai injection combined with chemotherapy in the treatment of lung cancer in the elderly helps to improve the clinical efficacy and quality of life of the patients, effectively control the stability of the disease, reduce the incidence of adverse reactions, so it is worthy of further promotion in clinical practice.
