中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
30期
8-9,33
,共3页
进展性脑卒中%阿司匹林%氯吡格雷
進展性腦卒中%阿司匹林%氯吡格雷
진전성뇌졸중%아사필림%록필격뢰
Progressive stroke%Aspirin%Clopidogrel
目的：研究分析阿司匹林与氯吡格雷治疗进展性脑卒中的临床疗效。方法将该院2012年1月-2013年12月期间收治的进展性脑卒中患者随机抽取162例作为该次研究对象，按随机双盲法分为两组，对照组81例采用阿司匹林对其进行治疗，观察组81例在该基础上给予氯吡格雷对其进行治疗，两组患者疗程均为4周，对比两组患者的临床效果，同时对治疗前后的神经功能缺损程度进行评分。结果观察组治疗后总有效率为86.41%，明显高于对照组总有效率72.83%，差异有统计学意义(P<0.05）﹔两组患者治疗前神经功能缺损评分差异无统计学意义(P>0.05），治疗后观察组明显优于对照组，差异有统计学意义(P<0.05）。结论阿司匹林与氯吡格雷治疗进展性脑卒中疗效较好，对改善患者的神经功能缺损程度较为明显，且安全性较高，值得在临床上推广应用。
目的：研究分析阿司匹林與氯吡格雷治療進展性腦卒中的臨床療效。方法將該院2012年1月-2013年12月期間收治的進展性腦卒中患者隨機抽取162例作為該次研究對象，按隨機雙盲法分為兩組，對照組81例採用阿司匹林對其進行治療，觀察組81例在該基礎上給予氯吡格雷對其進行治療，兩組患者療程均為4週，對比兩組患者的臨床效果，同時對治療前後的神經功能缺損程度進行評分。結果觀察組治療後總有效率為86.41%，明顯高于對照組總有效率72.83%，差異有統計學意義(P<0.05）﹔兩組患者治療前神經功能缺損評分差異無統計學意義(P>0.05），治療後觀察組明顯優于對照組，差異有統計學意義(P<0.05）。結論阿司匹林與氯吡格雷治療進展性腦卒中療效較好，對改善患者的神經功能缺損程度較為明顯，且安全性較高，值得在臨床上推廣應用。
목적：연구분석아사필림여록필격뢰치료진전성뇌졸중적림상료효。방법장해원2012년1월-2013년12월기간수치적진전성뇌졸중환자수궤추취162례작위해차연구대상，안수궤쌍맹법분위량조，대조조81례채용아사필림대기진행치료，관찰조81례재해기출상급여록필격뢰대기진행치료，량조환자료정균위4주，대비량조환자적림상효과，동시대치료전후적신경공능결손정도진행평분。결과관찰조치료후총유효솔위86.41%，명현고우대조조총유효솔72.83%，차이유통계학의의(P<0.05）﹔량조환자치료전신경공능결손평분차이무통계학의의(P>0.05），치료후관찰조명현우우대조조，차이유통계학의의(P<0.05）。결론아사필림여록필격뢰치료진전성뇌졸중료효교호，대개선환자적신경공능결손정도교위명현，차안전성교고，치득재림상상추엄응용。
Objective To study and analyze the clinical curative effect of aspirin and clopidogrel in the treatment of progressive stroke. Methods 162 cases with progressive stroke admitted in our hospital from January 2012 to December 2013 were randomly selected as the subjects of this study and divided into two groups according to the randomized and double-blinded method. 81 cas-es in the control group were treated by aspirin, and 81 cases in the observation group were treated by clopidogrel on the basis of aspirin. Both groups were treated for 4 weeks. The clinical effects were compared between two groups. And the degree of neurolog-ical deficit of the two groups before and after treatment was evaluated. Results After treatment, the total effective rate of the obser-vation group was 86.41%, significantly higher than 72.83% of the control group, the difference was statistically significant (P<0.05); before treatment, the difference in neurological deficit score between the two groups was not statistically significant(P>0.05), after treatment, the observation group was significantly better than the control group with statistical difference (P<0.05). Conclu-sion Both aspirin and clopidogrel have good effect on progressive stroke, they can obviously improve the neurological deficit of the patients with high safety, and are worthy of clinical application and promotion.
