CAJ | 학술논문

目的：探讨ARB联合ACEI用于陈旧性心肌梗死合并心衰中的临床疗效。方法该研究选择了2011年5月-2013年5月期间该院收治的80例在院内治疗的陈旧型心梗合并心衰患者作为主要研究对象。采用随机的方法将这些患者分为对照组和研究组，每组40例患者。对照组患者采用常规的治疗方法进行治疗，研究组患者在常规治疗的基础上再用坎地沙坦酯片加马来酸依那普利片进行结合治疗，在治疗过后，观察比较两组的临床治疗效果，并对两组患者的临床效果资料行分析研究。结果通过10个月的治疗，对两组患者的各项指标行治疗前后的比较，其中患者的左室舒张末容积，左室射血分数及hs-CRP的水平都比治疗前有所改善，差异有统计学意义(P<0.05）。结论ARB联合ACEI治疗陈旧性心肌梗死合并心衰疗效明显，临床治疗推广可行性高。
목적：탐토ARB연합ACEI용우진구성심기경사합병심쇠중적림상료효。방법해연구선택료2011년5월-2013년5월기간해원수치적80례재원내치료적진구형심경합병심쇠환자작위주요연구대상。채용수궤적방법장저사환자분위대조조화연구조，매조40례환자。대조조환자채용상규적치료방법진행치료，연구조환자재상규치료적기출상재용감지사탄지편가마래산의나보리편진행결합치료，재치료과후，관찰비교량조적림상치료효과，병대량조환자적림상효과자료행분석연구。결과통과10개월적치료，대량조환자적각항지표행치료전후적비교，기중환자적좌실서장말용적，좌실사혈분수급hs-CRP적수평도비치료전유소개선，차이유통계학의의(P<0.05）。결론ARB연합ACEI치료진구성심기경사합병심쇠료효명현，림상치료추엄가행성고。
Objective To explore the clinical curative effect and efficacy of ARB combined with ACEI for old myocardial infarction complicated by heart failure. Methods 80 cases with old myocardial infarction complicated by heart failure treated in our hospital from May 2011 to May 2013 were selected as the main subjects and randomly divided into the control group and the study group with 40 cases in each. Patients in the control group were treated by the conventional method, and patients in the study group were treated by Candesartan Ester Tablets and Enalapril Maleate Tablets on the basis of the conventional treatment. After treatment, the clinical curative effects of the two groups were observed and compared. And the data of clinical effects of the two groups were ana-lyzed and studied. Results The comparison of the indicators of the two groups before treatment and after 10 months of treatment showed that the left ventricular end diastolic volume, left ventricular ejection fraction and hs-CRP levels of the patients were all im-proved compared with those before treatment, the differences were statistically significant, P<0.05. Conclusion ARB combined with ACEI is quite effective in treating old myocardial infarction complicated by heart failure with high feasibility of clinical promotion.