CAJ | 학술논문

目的：研究中西医结合和单纯化化疗治疗中晚期胃癌的效果差异,为临床治疗提供参考。方法选取该院2012年3月-2013年3月收治的122例中晚期胃癌患者为研究对象,随机分为对照组和实验组各61例。对照组给予常规化疗,治疗组加用健脾益气的中药调理。比较对照组和实验组患者的临床疗效,治疗4周后的临床症状发生情况,并随访1年,比较患者存活率。结果两组临床疗效比较,实验组有效率为53.4%,对照组为28.4%；实验组临床症状发生情况明显降低；实验组半年生存率为86.6%,1年生存率为58.4%,对照组分别为56.6%,25.1%；差异有统计学意义(P<0.05)。结论采用中西医结合治疗中晚期胃癌比单纯化疗治疗效果更好,适合在临床长期推广应用。
목적：연구중서의결합화단순화화료치료중만기위암적효과차이,위림상치료제공삼고。방법선취해원2012년3월-2013년3월수치적122례중만기위암환자위연구대상,수궤분위대조조화실험조각61례。대조조급여상규화료,치료조가용건비익기적중약조리。비교대조조화실험조환자적림상료효,치료4주후적림상증상발생정황,병수방1년,비교환자존활솔。결과량조림상료효비교,실험조유효솔위53.4%,대조조위28.4%；실험조림상증상발생정황명현강저；실험조반년생존솔위86.6%,1년생존솔위58.4%,대조조분별위56.6%,25.1%；차이유통계학의의(P<0.05)。결론채용중서의결합치료중만기위암비단순화료치료효과경호,괄합재림상장기추엄응용。
Objective To study the difference in the effect of combination of traditional Chinese and western medicine with that of chemotherapy alone in the treatment of advanced gastric cancer, so as to provide a reference for the clinical treatment. Methods 122 patients with advanced gastric cancer admitted in our hospital from March 2012 to March 2013 were selected as the subjects and randomly divided into the control group and the experimental group with 61 cases in each. The control group was treated with the conventional chemotherapy, and the treatment group was treated with the traditional Chinese medicine for strengthening the spleen and replenishing qi based on the conventional chemotherapy. The clinical curative effect, clinical symptoms after 4 weeks of treatment, and the survival rate showed by 1-year follow-up were compared between the control group and the experimental group. Results Comparing the clinical curative effect of the two groups, the effective rate of the experimental group was 53.4%, and that of the control group was 28.4%;the clinical symptoms of the experimental group were significantly less; the half-year, 1-year sur-vival rate of the experimental group was 86.6%, 58.4%, respectively, and that of the control group was 56.6%, 25.1%, respectively;the differences were all statistically significant(P<0.05). Conclusion For advanced gastric cancer, the combination of traditional Chinese and western medicine has better effect than chemotherapy alone, which is suitable for long-term clinical application and promotion.