中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
12期
73-75
,共3页
狄淬砺%赵亚群%王永%梁晋川
狄淬礪%趙亞群%王永%樑晉川
적쉬려%조아군%왕영%량진천
肿瘤%腰大池置管持续引流%颅内感染%临床效果
腫瘤%腰大池置管持續引流%顱內感染%臨床效果
종류%요대지치관지속인류%로내감염%림상효과
Tumor%Lumbar catheter drainage of cisterna magna%Intracranial infection%Clinical efifcacy
目的：探究腰大池置管持续引流联合鞘内注射用药治疗颅内肿瘤术后颅内感染的临床效果。方法回顾性分析2010年1月至2013年12月本院门诊收入的颅内肿瘤术后颅内感染50例患者的临床资料。记录并分析患者治疗前后颅内压、脑脊液中葡萄糖、蛋白质、白细胞、氯化钠含量及治疗情况。结果50例患者治愈42例，显效3例，好转4例，无效1例，总有效率为98.0%（49/50）。治疗后颅内压及脑脊液中葡萄糖、白细胞、氯化钠、蛋白质含量较治疗前均有不同程度的变化，差异具有显著性（P＜0.05）。治疗过程中，患者静脉用药时间为8～20天，平均（12.5±2.3）天；置管引流时间为5～15天，平均（7.3±1.8）天；鞘内注射次数为5～13次，平均（6.7±1.2）次。结论腰大池置管持续引流联合鞘内注射用药治疗颅内肿瘤术后颅内感染效果显著，可明显降低颅内压，促进患者康复，且操作简单、方便，具有较高的临床应用价值。
目的：探究腰大池置管持續引流聯閤鞘內註射用藥治療顱內腫瘤術後顱內感染的臨床效果。方法迴顧性分析2010年1月至2013年12月本院門診收入的顱內腫瘤術後顱內感染50例患者的臨床資料。記錄併分析患者治療前後顱內壓、腦脊液中葡萄糖、蛋白質、白細胞、氯化鈉含量及治療情況。結果50例患者治愈42例，顯效3例，好轉4例，無效1例，總有效率為98.0%（49/50）。治療後顱內壓及腦脊液中葡萄糖、白細胞、氯化鈉、蛋白質含量較治療前均有不同程度的變化，差異具有顯著性（P＜0.05）。治療過程中，患者靜脈用藥時間為8～20天，平均（12.5±2.3）天；置管引流時間為5～15天，平均（7.3±1.8）天；鞘內註射次數為5～13次，平均（6.7±1.2）次。結論腰大池置管持續引流聯閤鞘內註射用藥治療顱內腫瘤術後顱內感染效果顯著，可明顯降低顱內壓，促進患者康複，且操作簡單、方便，具有較高的臨床應用價值。
목적：탐구요대지치관지속인류연합초내주사용약치료로내종류술후로내감염적림상효과。방법회고성분석2010년1월지2013년12월본원문진수입적로내종류술후로내감염50례환자적림상자료。기록병분석환자치료전후로내압、뇌척액중포도당、단백질、백세포、록화납함량급치료정황。결과50례환자치유42례，현효3례，호전4례，무효1례，총유효솔위98.0%（49/50）。치료후로내압급뇌척액중포도당、백세포、록화납、단백질함량교치료전균유불동정도적변화，차이구유현저성（P＜0.05）。치료과정중，환자정맥용약시간위8～20천，평균（12.5±2.3）천；치관인류시간위5～15천，평균（7.3±1.8）천；초내주사차수위5～13차，평균（6.7±1.2）차。결론요대지치관지속인류연합초내주사용약치료로내종류술후로내감염효과현저，가명현강저로내압，촉진환자강복，차조작간단、방편，구유교고적림상응용개치。
Objective To explore the clinical efficacy of lumbar catheter drainage of cisterna magna combining intrathecal injection medication treating intracranial infection of patients with intracranial tumor. Method Retrospective analysed the clinical data of 50 patients with intracranial infection after intracranial tumor operation in our hospital from January 2010 to December 2013. Analysed of patients before and after treatment of intracranial pressure, were the clinical indicators and treatment. Result 50 patients were cured in 42 cases, 3 cases were cured, 4 cases were improved, 1 case was ineffective, the total effective rate was 98.0% (49/50). After treatment of intracranial pressure and CSF glucose, leukocyte, sodium chloride, protein content than the treatment index before changes in varying degrees, the difference was significant (P<0.05). In the course of treatment, patients in intravenous medication time was 8~20 days, the average was (12.5±2.3) days;catheter drainage time was 5~15 days, the average was (7.3±1.8) days;intrathecal injection of number was 5 ~ 13 times, the average was (6.7±1.2) times. Conclusion Lumbar catheter drainage of cisterna magna combining intrathecal injection of amikacin delivers signiifcant efifcacy in treating post-operative intracranial infection, it can obviously reduce intracranial pressure, promote recovery of clinical indexes, and pose simple and convenient operation, making high value of clinical service.
