中国医学前沿杂志(电子版)
中國醫學前沿雜誌(電子版)
중국의학전연잡지(전자판)
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
12期
50-53
,共4页
经皮经肝食管胃底静脉栓塞术%肝硬化%消化道出血%临床治疗
經皮經肝食管胃底靜脈栓塞術%肝硬化%消化道齣血%臨床治療
경피경간식관위저정맥전새술%간경화%소화도출혈%림상치료
Percutaneous by liver stomach esophagus vein embolization%Liver cirrhosis%Alimentary tract hemorrhage%Clinic treatment
目的:观察肝硬化合并上消化道大出血患者采取经皮经肝食管胃底静脉栓塞术治疗的临床疗效。方法回顾性分析本院2011年9月至2012年5月采取经皮经肝食管胃底静脉栓塞术治疗的27例肝硬化合并上消化道大出血患者(术前肝功能评价均为Child-Pugh C级)的临床资料,观察其再出血率、肝功能变化情况、肝性脑病发生率、术后2年生存率、食管胃底静脉曲张程度的改变。结果经皮经肝食管胃底静脉栓塞术治疗肝硬化合并上消化道大出血手术成功率为100.0%,止血率为100.0%,1例患者术后次日因呼吸衰竭死亡。患者平均门静脉压力由术前(19.9±3.2)mmHg升至术后(22.7±4.7) mmHg,差异具有显著性(P<0.05)。患者平均随访时间为(27.4±3.6)个月,随访期间再出血率为26.9%(7/26),肝性脑病发生率为15.4%(4/26),术后2年生存率为84.6%。患者肝功能在术后3、6、12个月Child-Pugh评分下降,白蛋白水平上升,差异具有显著性(P<0.05)。结论经皮经肝食管胃底静脉栓塞术治疗肝硬化合并上消化道大出血能够及时止血,且患者术后再出血率、肝性脑病发生率较低,术后2年生存率较高,术后肝功能得到改善。经皮经肝食管胃底静脉栓塞术是治疗肝硬化合并上消化道大出血安全有效的方法,具有重要的临床应用价值。
目的:觀察肝硬化閤併上消化道大齣血患者採取經皮經肝食管胃底靜脈栓塞術治療的臨床療效。方法迴顧性分析本院2011年9月至2012年5月採取經皮經肝食管胃底靜脈栓塞術治療的27例肝硬化閤併上消化道大齣血患者(術前肝功能評價均為Child-Pugh C級)的臨床資料,觀察其再齣血率、肝功能變化情況、肝性腦病髮生率、術後2年生存率、食管胃底靜脈麯張程度的改變。結果經皮經肝食管胃底靜脈栓塞術治療肝硬化閤併上消化道大齣血手術成功率為100.0%,止血率為100.0%,1例患者術後次日因呼吸衰竭死亡。患者平均門靜脈壓力由術前(19.9±3.2)mmHg升至術後(22.7±4.7) mmHg,差異具有顯著性(P<0.05)。患者平均隨訪時間為(27.4±3.6)箇月,隨訪期間再齣血率為26.9%(7/26),肝性腦病髮生率為15.4%(4/26),術後2年生存率為84.6%。患者肝功能在術後3、6、12箇月Child-Pugh評分下降,白蛋白水平上升,差異具有顯著性(P<0.05)。結論經皮經肝食管胃底靜脈栓塞術治療肝硬化閤併上消化道大齣血能夠及時止血,且患者術後再齣血率、肝性腦病髮生率較低,術後2年生存率較高,術後肝功能得到改善。經皮經肝食管胃底靜脈栓塞術是治療肝硬化閤併上消化道大齣血安全有效的方法,具有重要的臨床應用價值。
목적:관찰간경화합병상소화도대출혈환자채취경피경간식관위저정맥전새술치료적림상료효。방법회고성분석본원2011년9월지2012년5월채취경피경간식관위저정맥전새술치료적27례간경화합병상소화도대출혈환자(술전간공능평개균위Child-Pugh C급)적림상자료,관찰기재출혈솔、간공능변화정황、간성뇌병발생솔、술후2년생존솔、식관위저정맥곡장정도적개변。결과경피경간식관위저정맥전새술치료간경화합병상소화도대출혈수술성공솔위100.0%,지혈솔위100.0%,1례환자술후차일인호흡쇠갈사망。환자평균문정맥압력유술전(19.9±3.2)mmHg승지술후(22.7±4.7) mmHg,차이구유현저성(P<0.05)。환자평균수방시간위(27.4±3.6)개월,수방기간재출혈솔위26.9%(7/26),간성뇌병발생솔위15.4%(4/26),술후2년생존솔위84.6%。환자간공능재술후3、6、12개월Child-Pugh평분하강,백단백수평상승,차이구유현저성(P<0.05)。결론경피경간식관위저정맥전새술치료간경화합병상소화도대출혈능구급시지혈,차환자술후재출혈솔、간성뇌병발생솔교저,술후2년생존솔교고,술후간공능득도개선。경피경간식관위저정맥전새술시치료간경화합병상소화도대출혈안전유효적방법,구유중요적림상응용개치。
Objective To observe hepatocirrhosis with upper gastrointestinal hemorrhage patients take percutaneous by liver stomach esophagus vein embolization clinical curative effect. Method The clinical information of 27 patients were retrospectively analyzed in our hospital from September 2011 to May 2012, whom with hepatocirrhosis with massive hemorrhage of upper gastrointestinal tract (preoperative evaluation of liver function are all Child-Pugh C level) to percutaneous by liver stomach esophagus vein embolization, observed the bleeding rate and liver function changes again, the incidence of hepatic encephalopathy, 2 years survival rate, the change of the degree of esophageal gastric varices. Result Percutaneous by liver stomach esophagus vein embolization hepatocirrhosis with massive hemorrhage of upper gastrointestinal tract surgery success rate was 100.0%, the bleeding rate was 100.0%, 1 case died of respiratory failure day later. Patients with an average of portal vein pressure rose from preoperative (19.9±3.2) mmHg to postoperative (22.7±4.7) mmHg, which was signiifcant difference (P<0.05). Patients with an average time of follow-up was (27.4±3.6) months follow-up period to hemorrhage rate was 26.9%(7/26), the incidence of hepatic encephalopathy was 15.4%(4/26), postoperative 2 years survival rate ofter surgery was 84.6%. Liver function in patients with postoperative 3, 6, 12 months Child-Pugh score declined, albumin levels rose, with signiifcant difference (P < 0.05). Conclusion Percutaneous by liver stomach esophagus vein embolization hepatocirrhosis with massive hemorrhage of upper gastrointestinal tract can timely hemostasia, and patients with postoperative rebleeding rate and low incidence of hepatic encephalopathy, 2 years survival rate after surgery is higher, liver function improved after surgery. Percutaneous liver stomach esophagus vein embolization is safe and effective for the treatment of hepatocirrhosis with upper gastrointestinal hemorrhage in the method, has important value of clinical application.