中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
12期
44-46
,共3页
硝苯地平缓释片%高血压%糖尿病
硝苯地平緩釋片%高血壓%糖尿病
초분지평완석편%고혈압%당뇨병
Nifedipine sustained-release tablets%Hypertension%Diabetes mellitus
目的：对比硝苯地平缓释片及依那普利对高血压合并糖尿病的临床治疗效果。方法选取2013年2月至2014年2月于本院住院治疗的86例高血压合并糖尿病患者为研究对象，随机分为对照组和观察组，每组各43例。观察组患者在常规治疗基础上加用硝苯地平缓释片，对照组患者在常规治疗基础上加用依那普利。比较两组患者治疗前后血压、心率、血尿素氮、血肌酐水平及疗效。结果观察组患者治疗总有效率为95.35%（41/43），对照组为74.42%（32/43），观察组显著高于对照组（P＜0.05）；两组患者治疗后血压均较治疗前显著下降，且观察组优于对照组（P＜0.05）；两组患者治疗前后血尿素氮、血肌酐和心率比较差异均无显著性。结论硝苯地平缓释片对高血压合并糖尿病的治疗效果优于依那普利，且不影响糖、脂代谢与心血管功能，可作为高血压合并糖尿病的理想降压药物。
目的：對比硝苯地平緩釋片及依那普利對高血壓閤併糖尿病的臨床治療效果。方法選取2013年2月至2014年2月于本院住院治療的86例高血壓閤併糖尿病患者為研究對象，隨機分為對照組和觀察組，每組各43例。觀察組患者在常規治療基礎上加用硝苯地平緩釋片，對照組患者在常規治療基礎上加用依那普利。比較兩組患者治療前後血壓、心率、血尿素氮、血肌酐水平及療效。結果觀察組患者治療總有效率為95.35%（41/43），對照組為74.42%（32/43），觀察組顯著高于對照組（P＜0.05）；兩組患者治療後血壓均較治療前顯著下降，且觀察組優于對照組（P＜0.05）；兩組患者治療前後血尿素氮、血肌酐和心率比較差異均無顯著性。結論硝苯地平緩釋片對高血壓閤併糖尿病的治療效果優于依那普利，且不影響糖、脂代謝與心血管功能，可作為高血壓閤併糖尿病的理想降壓藥物。
목적：대비초분지평완석편급의나보리대고혈압합병당뇨병적림상치료효과。방법선취2013년2월지2014년2월우본원주원치료적86례고혈압합병당뇨병환자위연구대상，수궤분위대조조화관찰조，매조각43례。관찰조환자재상규치료기출상가용초분지평완석편，대조조환자재상규치료기출상가용의나보리。비교량조환자치료전후혈압、심솔、혈뇨소담、혈기항수평급료효。결과관찰조환자치료총유효솔위95.35%（41/43），대조조위74.42%（32/43），관찰조현저고우대조조（P＜0.05）；량조환자치료후혈압균교치료전현저하강，차관찰조우우대조조（P＜0.05）；량조환자치료전후혈뇨소담、혈기항화심솔비교차이균무현저성。결론초분지평완석편대고혈압합병당뇨병적치료효과우우의나보리，차불영향당、지대사여심혈관공능，가작위고혈압합병당뇨병적이상강압약물。
Objective To compare the efifcacy of nifedipine and enalapril in patients with hyperteusion complicating diabetes. Method 86 patients with hyperteusion complicating diabetes selected from February 2013 to February 2014 were divided into control group and observation group, 43 cases in each group. Patients in observation group based on the conventional treatment were given nifedipine sustained-release tablets, control group based on the conventional treatment were given enalapril. Blood pressure, heart rate, blood urea nitrogen, blood creatinine and curative effect were compared between the two groups. Result The total effective rate of observation group was 95.35%(41/43), higher than that of control group 74.42%(32/43), the difference was signiifcant (P<0.05). The blood pressure after treatment was lower than that before treatment signiifcantly in two groups (P < 0.05). There were no signiifcant difference in two groups before and after treatment in patients with blood urea nitrogen, blood creatinine and heart rate. Conclusion The treatment effect of nifedipine sustained-release tablets in patients with hyperteusion complicating diabetes better than enalapril, and it has no side effect on glucose and lipid metabolism or cardiovascular function, so it can be choosen as the ideal drugs for diabetes mellitus and hypertension. remarkable.
