CAJ | 학술논문

目的：使用频域光学相干断层扫描（OCT）检测早期原发性开角型青光眼（POAG）视盘参数与视野平均缺损（MD）的相关性，评估频域OCT检测视盘参数在POAG早期诊断中的价值。方法正常人55例（55只眼）及早期POAG患者55例（55只眼）。采用Cirrus SD-OCT和Synemed EP-930自动视野计分别进行视盘形态和视野检测。 OCT检测采用optic disc cube 200×200模式，评估数据包括视盘面积、盘沿面积、平均杯盘比、垂直杯盘比及视杯容积。视野检测采用Synemed EP-930自动视野计30°-2程序。比较2组间视盘参数的差异，分析早期青光眼组MD数值与Cirrus SD-OCT视盘参数的关系。结果早期POAG组与正常组之间的视盘参数比较，除视盘面积外其余参数均存在统计学意义的差异（P＜0.001）。早期POAG组盘沿面积与视野MD相关性最好（r=0.561，P＜0.001）。结论频域OCT检测的视盘参数在POAG早期诊断中具有重要价值。
목적：사용빈역광학상간단층소묘（OCT）검측조기원발성개각형청광안（POAG）시반삼수여시야평균결손（MD）적상관성，평고빈역OCT검측시반삼수재POAG조기진단중적개치。방법정상인55례（55지안）급조기POAG환자55례（55지안）。채용Cirrus SD-OCT화Synemed EP-930자동시야계분별진행시반형태화시야검측。 OCT검측채용optic disc cube 200×200모식，평고수거포괄시반면적、반연면적、평균배반비、수직배반비급시배용적。시야검측채용Synemed EP-930자동시야계30°-2정서。비교2조간시반삼수적차이，분석조기청광안조MD수치여Cirrus SD-OCT시반삼수적관계。결과조기POAG조여정상조지간적시반삼수비교，제시반면적외기여삼수균존재통계학의의적차이（P＜0.001）。조기POAG조반연면적여시야MD상관성최호（r=0.561，P＜0.001）。결론빈역OCT검측적시반삼수재POAG조기진단중구유중요개치。
OBJECTIVE To study the correlation between optic disc parameters measured by Cirrus SD-OCT and visual field detect in early primary open-angle glaucoma (POAG). METHODS The tomography of optic nerve head was measured by Cirrus SD-OCT in 55 patients (55 eyes) with early POAG and 55 normal subjects 55 eyes. 3D cube OCT data was obtained using Opitic Disk Cube 200×200 Scan pattern, which performed raster scanning in a 6×6mm square centered on the opitic head composed of 200A-scans and 200B-scans. Disc area, rim area, average cup/disc ratio, vertical cup/disc ratio, and cup volume were evaluated. These ONH parameters were compared be-tween normal subjects and eyes with early POAG. All eyes were detected by Synemed EP-930 perimetry. The corre-lation between mean deviation and optic disc parameters in early POAG eyes was also analyzed. SPSS 17.0 statistical software was used for statistical analyses. RESULTS There were significant differences of all optic disc parameters between normal and early POAG eyes except disc area (P<0.001). Rim area had marked correlation with MD in ear-ly POAG eyes (r=0.562, P<0.001). CONCLUSIONS Measurement of optic disc parameters by Cirrus HD-OCT was useful in detecting early glaucomatous damage and had marked correlation with MD.