CAJ | 학술논문

目的：探讨中药复方治疗小儿神经性尿频的用药规律。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)中治疗小儿神经性尿频的文献，建立相应数据库。应用中医传承辅助系统(V2.0)，采用改进互信息法、复杂系统熵聚类、无监督熵层次聚类等无监督数据挖掘方法，分析小儿神经性尿频方剂的组方规律。结果63首处方中共包括117味药物，使用频次≥5次的药物有32味；2～3味药物组合模式共22组，包括10味药物；规则分析获得11组药物关联规则及其置信度，演化得到核心组合14个，新处方7个。结论中药复方治疗小儿神经性尿频多以补为用，多选用补肾固涩缩尿之品；生成的新处方还有待临床进一步验证。
목적：탐토중약복방치료소인신경성뇨빈적용약규률。방법검색중국지식자원총고(CNKI)、중문과기기간수거고(VIP)、중국학술기간수거고(만방수거)중치료소인신경성뇨빈적문헌，건립상응수거고。응용중의전승보조계통(V2.0)，채용개진호신식법、복잡계통적취류、무감독적층차취류등무감독수거알굴방법，분석소인신경성뇨빈방제적조방규률。결과63수처방중공포괄117미약물，사용빈차≥5차적약물유32미；2～3미약물조합모식공22조，포괄10미약물；규칙분석획득11조약물관련규칙급기치신도，연화득도핵심조합14개，신처방7개。결론중약복방치료소인신경성뇨빈다이보위용，다선용보신고삽축뇨지품；생성적신처방환유대림상진일보험증。
Objective To analyze the composing principles of herbs in prescriptions for treating nervous urinary frequency of children by using traditional Chinese medicine. Methods The prescriptions for treating nervous urinary frequency of children were searched in CNKI, VIP, Wanfang database to establish relevant database, and the composing principles were analyzed by using revised mutual information, complex system entropy cluster, and unsupervised hierarchical clustering in the TCM inheritance system after data entry. Results Based on the analysis of 117 entries in 63 cases of prescriptions, the frequency of 32 entries was more than 5 times;22 combinations contained 2 to 3 entries, including 10 entries in total 11 medicine association rules and their confidence coefficient were obtained, which leaded to 14 new core combinations and 7 new prescriptions. Conclusion Nervous urinary frequency of children is mainly treated with the tonification by Chinese herbal compound, in particular with the herbs which can nourish kidney and reduce urination. The new prescriptions were generated by TCM inheritance system, which need verification through clinical trials.