CAJ | 학술논문

目的：探讨子宫内膜息肉（ endometrial polyps ，EP）电切术后宫内放置左炔诺孕酮宫内缓释系统（ levonorgestrel intrauterine system ， LNG－IUS，又称曼月乐）预防息肉复发的临床疗效。方法收集整理2010年1月至2012年5月郑州市妇幼保健院收治的120例EP电切术后患者的临床资料，根据不同处理方法分为对照组45例、黄体酮组40例、曼月乐组35例。比较3组术后出血情况、术后2年EP复发情况。结果术后出血患者比例由高到低依次为：曼月乐组45.7％（16／35）、对照组33.3％（15／45）、黄体酮组22.5％（9／40）。术后2年曼月乐组复发率2.9％（1／35），低于对照组8.9％（4／45）及黄体酮组5.0％（2／40）（P＜0.05）。结论 EP电切术后宫内放置LNG－IUS预防息肉复发的疗效显著。
목적：탐토자궁내막식육（ endometrial polyps ，EP）전절술후궁내방치좌결낙잉동궁내완석계통（ levonorgestrel intrauterine system ， LNG－IUS，우칭만월악）예방식육복발적림상료효。방법수집정리2010년1월지2012년5월정주시부유보건원수치적120례EP전절술후환자적림상자료，근거불동처리방법분위대조조45례、황체동조40례、만월악조35례。비교3조술후출혈정황、술후2년EP복발정황。결과술후출혈환자비례유고도저의차위：만월악조45.7％（16／35）、대조조33.3％（15／45）、황체동조22.5％（9／40）。술후2년만월악조복발솔2.9％（1／35），저우대조조8.9％（4／45）급황체동조5.0％（2／40）（P＜0.05）。결론 EP전절술후궁내방치LNG－IUS예방식육복발적료효현저。
Objective To investigate the clinical efficacy of levonorgestrel intrauterine system ( LNG -IUS ) in preventing recurrence of endometrial polyp ( EP ) after endometrial polyp resection .Methods Data of 120 patients with endometrial polyp resection in Zhengzhou Maternal and Child Health Hospital from Jan 2010 to May 2012 were collected , all cases were divided into the control group (n=45), progesterone group (n=40), the Mirena group (n=35).The postoperative bleeding, recurrence rate of EP after 2 years between three groups were compared .Results The rate of postoperative bleeding from high to low were Mirena group 45.7%(16/35), control group 33.3% (15/45), progesterone group 22.5% (9/40).The recurrence rate of EP after 2 years in Mirena group was 2.9%(1/35), which was lower than the control group 8.9%(4/45) and progesterone group 5.0%(2/40) (P<0.05).Conclusion The effect of LNG-IUS in preventing recurrence of EP is remarkable after endometrial polyp resection .