中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
1期
162-164,174
,共4页
降钙素原%胎膜早破%C-反应蛋白%绒毛膜羊膜炎
降鈣素原%胎膜早破%C-反應蛋白%絨毛膜羊膜炎
강개소원%태막조파%C-반응단백%융모막양막염
Procalcitonin%Premature rupture of membranes%C-reactive protein%Chorioamnionitis
目的：探讨血清降钙素原检测在胎膜早破患者的临床应用价值。方法选择胎膜早破患者（实验组）和正常分娩组（对照组）各180例，采用电化学发光法检测两组孕妇血清PCT水平，采用散射比浊法检测CRP水平，产后取胎盘组织行组织病理学检查，根据病检结果分为绒毛膜羊膜炎组和非绒毛膜羊膜炎组。结果胎膜早破患者的PCT阳性率68.9%，明显高于正常孕妇组（阳性率15.6%），且差异有统计学意义（P=0.000）；CRP阳性率11.1%，PCT与CRP的阳性率比较差异有统计学意义（P=0.003），PCT反映感染的敏感度明显高于CRP，且二者的阳性率表达无相关性（P=0.080）；绒毛膜羊膜炎组PCT的阳性率（67.7%）高于非绒毛膜羊膜炎组（阳性率为32.2%），且差异有统计学意义（P＜0.05）。结论PCT可对胎膜早破孕妇并发绒毛膜羊膜炎进行早期预测并给予及时治疗，值得临床推广。
目的：探討血清降鈣素原檢測在胎膜早破患者的臨床應用價值。方法選擇胎膜早破患者（實驗組）和正常分娩組（對照組）各180例，採用電化學髮光法檢測兩組孕婦血清PCT水平，採用散射比濁法檢測CRP水平，產後取胎盤組織行組織病理學檢查，根據病檢結果分為絨毛膜羊膜炎組和非絨毛膜羊膜炎組。結果胎膜早破患者的PCT暘性率68.9%，明顯高于正常孕婦組（暘性率15.6%），且差異有統計學意義（P=0.000）；CRP暘性率11.1%，PCT與CRP的暘性率比較差異有統計學意義（P=0.003），PCT反映感染的敏感度明顯高于CRP，且二者的暘性率錶達無相關性（P=0.080）；絨毛膜羊膜炎組PCT的暘性率（67.7%）高于非絨毛膜羊膜炎組（暘性率為32.2%），且差異有統計學意義（P＜0.05）。結論PCT可對胎膜早破孕婦併髮絨毛膜羊膜炎進行早期預測併給予及時治療，值得臨床推廣。
목적：탐토혈청강개소원검측재태막조파환자적림상응용개치。방법선택태막조파환자（실험조）화정상분면조（대조조）각180례，채용전화학발광법검측량조잉부혈청PCT수평，채용산사비탁법검측CRP수평，산후취태반조직행조직병이학검사，근거병검결과분위융모막양막염조화비융모막양막염조。결과태막조파환자적PCT양성솔68.9%，명현고우정상잉부조（양성솔15.6%），차차이유통계학의의（P=0.000）；CRP양성솔11.1%，PCT여CRP적양성솔비교차이유통계학의의（P=0.003），PCT반영감염적민감도명현고우CRP，차이자적양성솔표체무상관성（P=0.080）；융모막양막염조PCT적양성솔（67.7%）고우비융모막양막염조（양성솔위32.2%），차차이유통계학의의（P＜0.05）。결론PCT가대태막조파잉부병발융모막양막염진행조기예측병급여급시치료，치득림상추엄。
Objective To discuss the clinical vaulue of PCT detection in patients with premature rupture of Membranes. Methods 180 cases of patients with premature rupture of membranes (experimental group )and patients of normal childbirth (control group), the serum level of PCT in two groups of pregnant women was detected through the method of electrochemical luminescence, Scattering turbidimetric method was used to detect CRP level, postpartum placental tissue was sent to histopathological examination ,according to inspection results , patients were divided into chorioamnionitis group and non chorioamnionitis group. Results The positive rates of PCT in pregnant women with PROM(68.9%) were significantly higher than those in control group(15.6%),and there was significant difference between the two groups; The positive rates of CRP were 11.1%, and there was significant difference between the positive rates of PCT and CRP.PCT levels are seemed to be more sensitive than CRP in the diagnostic of infection and there were no relationship between the positive rates of PCT and CRP. The positive rates of PCT in pregnant women with chorioamnionitis group (67.7%) were significantly higher than those in control group (32.2%), and there was significant difference between the two groups. Conclusion PCT has important clinical guiding significance on early prediction and treatment in pregnant women with PROM and chorioamnionitis, and it has clinical promotion significance.
