CAJ | 학술논문

目的：探讨血清标志物CA153、CA125、CEA、CA199的在早期乳腺癌诊断中的临床应用价值。方法：采用化学发光免疫分析检测法测定37例乳腺良性病变以及52例Ⅰ、Ⅱ期乳腺癌患者治疗前血清CA153、CA125、CEA、CA199的检测值。结果：CA153、CA199的测定值明显高于良性肿瘤组(P<0．05)，乳腺癌组中CA153、CA199阳性检测率以及四者之一阳性检测率与正常对照组相比较有显著性差异(P<0．05)。结论：联合四项检测对乳腺癌Ⅰ、Ⅱ期的敏感性和准确性优于单项检测，可以互相弥补单一指标的不足。
목적：탐토혈청표지물CA153、CA125、CEA、CA199적재조기유선암진단중적림상응용개치。방법：채용화학발광면역분석검측법측정37례유선량성병변이급52례Ⅰ、Ⅱ기유선암환자치료전혈청CA153、CA125、CEA、CA199적검측치。결과：CA153、CA199적측정치명현고우량성종류조(P<0．05)，유선암조중CA153、CA199양성검측솔이급사자지일양성검측솔여정상대조조상비교유현저성차이(P<0．05)。결론：연합사항검측대유선암Ⅰ、Ⅱ기적민감성화준학성우우단항검측，가이호상미보단일지표적불족。
Objective To investigate the serum markers of CA153, CA125,CEA, CA199 in the early diagnosis of breast cancer and clinical application value. Chemiluminescence immunoassay detectionmethod For the determination of 37 cases of benign breast lesions and 52 cases of I, IIbreast cancer patients before treatment the serum CA153 detection,CA125, CEA, CA199 parameters by using the method. The results of determination of CA153, CA199 values were significantly higher than that ofbenign tumor group (P< 0.05), breast cancer in the group of CA153,CA199 positive detection rate and a four positive detection rate compared with the control group with significant difference (P< 0.05).Conclusion The combined four detection sensitivity and accuracy is beter than the single detection of breast cancer, 1 phase II, deficiencies can compensate each other single indicator.