上海预防医学
上海預防醫學
상해예방의학
SHANGHAI JOURNAL OF PREVENTIVE MEDICINE
2015年
2期
105-107
,共3页
子宫腺肌病%促性腺激素释放激素类似物%左炔诺孕酮宫内缓释系统
子宮腺肌病%促性腺激素釋放激素類似物%左炔諾孕酮宮內緩釋繫統
자궁선기병%촉성선격소석방격소유사물%좌결낙잉동궁내완석계통
Adenomyosis%Gonadotropin-releasing hormone analogues%Levonorgestrel releasing intrauterine system
[目的]探讨促性腺激素释放激素类似物( GnRHa)联合左炔诺孕酮宫内缓释系统( LNG-IUS)治疗子宫腺肌病(AM)的临床疗效。[方法]将70例AM患者随机分为观察组(n=34,GnRHa联合LNG-IUS治疗)与对照组(n=36,采用LNG-IUS治疗),比较两组患者治疗后子宫体积、痛经程度及月经过多等症状的改善情况。[结果]治疗后,子宫体积、痛经程度评分及月经量观察组明显低于或少于对照组,差异有统计学意义(P<0.05);对照组随访期间共出现7例(20.58%)阴道流血淋漓不尽,4例(11.76%)发生脱环;观察组则无阴道流血淋漓不尽情况及脱环发生。[结论] GnRHa联合LNG-IUS治疗与单纯放置LNG-IUS治疗相比,可以更有效治疗AM,缓解临床症状。
[目的]探討促性腺激素釋放激素類似物( GnRHa)聯閤左炔諾孕酮宮內緩釋繫統( LNG-IUS)治療子宮腺肌病(AM)的臨床療效。[方法]將70例AM患者隨機分為觀察組(n=34,GnRHa聯閤LNG-IUS治療)與對照組(n=36,採用LNG-IUS治療),比較兩組患者治療後子宮體積、痛經程度及月經過多等癥狀的改善情況。[結果]治療後,子宮體積、痛經程度評分及月經量觀察組明顯低于或少于對照組,差異有統計學意義(P<0.05);對照組隨訪期間共齣現7例(20.58%)陰道流血淋巑不儘,4例(11.76%)髮生脫環;觀察組則無陰道流血淋巑不儘情況及脫環髮生。[結論] GnRHa聯閤LNG-IUS治療與單純放置LNG-IUS治療相比,可以更有效治療AM,緩解臨床癥狀。
[목적]탐토촉성선격소석방격소유사물( GnRHa)연합좌결낙잉동궁내완석계통( LNG-IUS)치료자궁선기병(AM)적림상료효。[방법]장70례AM환자수궤분위관찰조(n=34,GnRHa연합LNG-IUS치료)여대조조(n=36,채용LNG-IUS치료),비교량조환자치료후자궁체적、통경정도급월경과다등증상적개선정황。[결과]치료후,자궁체적、통경정도평분급월경량관찰조명현저우혹소우대조조,차이유통계학의의(P<0.05);대조조수방기간공출현7례(20.58%)음도류혈림리불진,4례(11.76%)발생탈배;관찰조칙무음도류혈림리불진정황급탈배발생。[결론] GnRHa연합LNG-IUS치료여단순방치LNG-IUS치료상비,가이경유효치료AM,완해림상증상。
combined with LNG-IUS) and control group ( n =36, treated by only LNG-IUS).After treatment were compared the improvement of uterine volume , dysmenorrhea and menorrhagia and other symptoms in the two groups. [Results] After treatment, the uterine volume, dysmenorrhea severity score and menstrual flow in observation group were significantly lower than those in control group ( P<0.05);during follow-up time, there occurred 7 cases(20.58%) of dripping vaginal bleeding and 4 cases(11.76%) of decyclization in control group , while in observation group there was none of occurrence . [ Conclusion ] GnRHa combined with LNG-IUS is of better clinical efficacy in the treatment of adenomyosis than LNG-IUS used alone.