CAJ | 학술논문

目的：探讨血清 CEA，CA125，HE4，CA724联合检测对早期卵巢癌患者诊断的临床价值。方法：选取45例健康体检者、45例卵巢癌患者和45例卵巢良性病变患者，采用酶联免疫法对所有患者血清 CEA，CA125，HE4和CA724进行检测。结果：CEA，CA125，HE4和 CA724水平卵巢癌患者血清明显比健康患者和卵巢良性病变患者水平高，组间比较差异有统计学意义，P ﹤0.05；健康体检者血清与卵巢良性病变患者比较，差异无统计学意义，P ﹥0.05。结论：血清 CEA，CA125，HE4和 CA724联合检测对早期卵巢癌患者诊断具有重要意义。
목적：탐토혈청 CEA，CA125，HE4，CA724연합검측대조기란소암환자진단적림상개치。방법：선취45례건강체검자、45례란소암환자화45례란소량성병변환자，채용매련면역법대소유환자혈청 CEA，CA125，HE4화CA724진행검측。결과：CEA，CA125，HE4화 CA724수평란소암환자혈청명현비건강환자화란소량성병변환자수평고，조간비교차이유통계학의의，P ﹤0.05；건강체검자혈청여란소량성병변환자비교，차이무통계학의의，P ﹥0.05。결론：혈청 CEA，CA125，HE4화 CA724연합검측대조기란소암환자진단구유중요의의。
Objective:To investigate the clinical value of detecting the seruM levels of CEA,CA125,HE4 and CA724 for early diagnosis of ovarian cancer patients. Methods:SeruM CEA,CA125,HE4 and CA724 were detected by enzyMe - linked iMMunosorbent assay in subjects,including 45 healthy subjects,45 patients with ovarian cancer and 45 cases of ovarian benign disease patients. Results:CoMpared with the seruM levels of CEA,CA125,HE4 and CA724 in healthy subjects and patients with benign ovarian,that was higher in patients with ovarian cancer. There was significant difference between group,P ﹤ 0. 05. However,no significant difference in seruM levels of CEA,CA125,HE4 and CA724 were detected between healthy subjects and patients with ovarian benign lesions,P ﹥ 0. 05. Conclusion:The joint detection of CEA,CA125,HE4 and CA724 play an iM-portant role in the early diagnosis of patients with ovarian cancer. can increase the detection rate of early ovarian cancer,suit-able for clinical use.