广东医学
廣東醫學
엄동의학
GUNAGDONG MEDICAL JOURNAL
2015年
1期
16-19
,共4页
抑郁症%述情障碍%功能性躯体不适
抑鬱癥%述情障礙%功能性軀體不適
억욱증%술정장애%공능성구체불괄
depression%alexithymia%somatization
目的了解抑郁症患者功能性躯体不适症状的特征,并探讨抑郁症患者述情障碍与功能性躯体不适症状之间的关系。方法选用多伦多述情障碍量表20项中文版(TAS -20)、患者健康问卷(PHQ -15)和汉密尔顿抑郁量表17项版本(HAMD -17),对113例抑郁症患者(抑郁症组)和100例健康志愿者(对照组)进行评定。结果(1)抑郁症组 TAS -20总分及各因子分、 PHQ -15总分及各条目分均显著高于对照组(均 P <0.05);(2)根据 PHQ 总分将功能性躯体不适分为轻、中、重度,抑郁症组 TAS -20总分、情感辨别不能因子分和外向性思维因子分均依次升高(P <0.05);(3)情感辨别不能因子主要与四肢躯干疼痛及疲劳症状呈正相关(r =0.211,r =0.434,均P <0.05),外向性思维因子与头部及消化系不适呈正相关(r =0.192,r =0.388,均 P <0.05);(4)多元线性回归分析显示,情感辨别不能(β=0.220,95%CI 20.55~22.28)、外向性思维(β=0.216,95%CI 21.32~22.76)和 HAMD -17总分(β=0.334,95%CI 21.54~23.79)为功能性躯体不适的影响因素(R 2=0.238)。结论抑郁症患者存在严重而广泛的功能性躯体不适症状,情感辨别不能和外向性思维可能对部分症状的产生具有影响。
目的瞭解抑鬱癥患者功能性軀體不適癥狀的特徵,併探討抑鬱癥患者述情障礙與功能性軀體不適癥狀之間的關繫。方法選用多倫多述情障礙量錶20項中文版(TAS -20)、患者健康問捲(PHQ -15)和漢密爾頓抑鬱量錶17項版本(HAMD -17),對113例抑鬱癥患者(抑鬱癥組)和100例健康誌願者(對照組)進行評定。結果(1)抑鬱癥組 TAS -20總分及各因子分、 PHQ -15總分及各條目分均顯著高于對照組(均 P <0.05);(2)根據 PHQ 總分將功能性軀體不適分為輕、中、重度,抑鬱癥組 TAS -20總分、情感辨彆不能因子分和外嚮性思維因子分均依次升高(P <0.05);(3)情感辨彆不能因子主要與四肢軀榦疼痛及疲勞癥狀呈正相關(r =0.211,r =0.434,均P <0.05),外嚮性思維因子與頭部及消化繫不適呈正相關(r =0.192,r =0.388,均 P <0.05);(4)多元線性迴歸分析顯示,情感辨彆不能(β=0.220,95%CI 20.55~22.28)、外嚮性思維(β=0.216,95%CI 21.32~22.76)和 HAMD -17總分(β=0.334,95%CI 21.54~23.79)為功能性軀體不適的影響因素(R 2=0.238)。結論抑鬱癥患者存在嚴重而廣汎的功能性軀體不適癥狀,情感辨彆不能和外嚮性思維可能對部分癥狀的產生具有影響。
목적료해억욱증환자공능성구체불괄증상적특정,병탐토억욱증환자술정장애여공능성구체불괄증상지간적관계。방법선용다륜다술정장애량표20항중문판(TAS -20)、환자건강문권(PHQ -15)화한밀이돈억욱량표17항판본(HAMD -17),대113례억욱증환자(억욱증조)화100례건강지원자(대조조)진행평정。결과(1)억욱증조 TAS -20총분급각인자분、 PHQ -15총분급각조목분균현저고우대조조(균 P <0.05);(2)근거 PHQ 총분장공능성구체불괄분위경、중、중도,억욱증조 TAS -20총분、정감변별불능인자분화외향성사유인자분균의차승고(P <0.05);(3)정감변별불능인자주요여사지구간동통급피로증상정정상관(r =0.211,r =0.434,균P <0.05),외향성사유인자여두부급소화계불괄정정상관(r =0.192,r =0.388,균 P <0.05);(4)다원선성회귀분석현시,정감변별불능(β=0.220,95%CI 20.55~22.28)、외향성사유(β=0.216,95%CI 21.32~22.76)화 HAMD -17총분(β=0.334,95%CI 21.54~23.79)위공능성구체불괄적영향인소(R 2=0.238)。결론억욱증환자존재엄중이엄범적공능성구체불괄증상,정감변별불능화외향성사유가능대부분증상적산생구유영향。
Objective To examine the alexithymia features of patients with depressive disorder and to investigate the associations between alexithymia and somatization .Methods 113 patients with depressive disorder and 100 healthy controls were included.The Chinese version of the 20 -item Toronto Alexithymia Scale (TAS -20), Patient Health Ques-tionnaire (PHQ -15), and the 17 -item Hamilton Depression Scale (HAMD -17) were applied for analysis.Results Compared with controls, patients with depressive disorder showed significantly higher scores in TAS -20 and PHQ -15 (P <0.05).Among the scores of TAS -20, Factor 1 (difficulty in identifying feelings) and Factor 3 (externally oriented thinking) were gradually increased as the increased severity of somatization (P <0.05).In all three factors of alexithy-mia, Factor 1 was strongly correlated with symptoms of pain on body (including back and arms /legs/joints) and tire (r =0.211, r =0.434, P <0.05), while Factor 3 was strongly correlated with discomfort of digestive system and head (r =0.192, r =0.388, P <0.05).According to multiple linear regression, Factor 1 (β=0.220, 95%CI 20.55 ~22.28), Factor 3 (β=0.216, 95%CI 21.32 ~22.76) and HAMD -17 total scores (β=0.334, 95%CI 21.54 ~23.79) were the potential risk factors of somatic complains (R2 =0.238).Conclusion These results suggest that patients with de -pressive disorder have significant somatic amplifications .Alexithymia may be an affecting factor of the somatization symp -toms of depression.