CAJ | 학술논문

目的：观察颅脑外伤并发高钠血症连续性血液净化的临床疗效，分析探讨其对血清钠和血流动力学的影响。方法：选择我院2012年1月～2013年12月收治的28例脑外伤并发高钠血症患者为研究对象，给予连续性血液净化治疗，观察其治疗前、后的血清钠水平、血清钠纠正速度及血流动力学。结果：本组治疗有效率为92．86％，治疗后，患者血清钠水平明显降低（ P＜0．05），且心率、平均动脉压及氧合指数均得到明显改善（P＜0．05）。结论：连续性血液净化能够有效地调节颅脑外伤并发高钠血症患者的血清钠水平，纠正患者的电解质紊乱现象，改善预后，值得临床广泛推广。
목적：관찰로뇌외상병발고납혈증련속성혈액정화적림상료효，분석탐토기대혈청납화혈류동역학적영향。방법：선택아원2012년1월～2013년12월수치적28례뇌외상병발고납혈증환자위연구대상，급여련속성혈액정화치료，관찰기치료전、후적혈청납수평、혈청납규정속도급혈류동역학。결과：본조치료유효솔위92．86％，치료후，환자혈청납수평명현강저（ P＜0．05），차심솔、평균동맥압급양합지수균득도명현개선（P＜0．05）。결론：련속성혈액정화능구유효지조절로뇌외상병발고납혈증환자적혈청납수평，규정환자적전해질문란현상，개선예후，치득림상엄범추엄。
Objective:To study the clinical effect of continuous renal replacement therapy ( CRRT) in treatment of hypernatremia in patients with severe head injury and analyze the changes of serum sodium and hemodynamic.Methods:From 2012 January to 2013 De-cember our hospital, 28 cases of brain trauma complicated with hypernatremia patients as the research object, For the continuous blood purification treatment, were observed before and after treatment, serum sodium, serum sodium correction speed and hemodynamics.Re-sults:The effective rate of the treatment group was 92.86%, after treatment, serum sodium levels were significantly reduced (P<0.05), heart rate, mean arterial pressure, oxygenation index were significantly improved (P<0.05).Conclusion:CRRT in treatment of hyper-natremia in patients with severe head injury has curative effect, and is worth of clinical widely.